Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis
Liu, A., Yan, H., Wu, Y., Li, Y., Liu, J.To be published.
Experimental Data Snapshot
wwPDB Validation   3D Report Full Report
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
HCG40889, isoform CRA_b | 61 | Homo sapiens | Mutation(s): 0  Gene Names: hCG_40889 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P08603 (Homo sapiens) Explore P08603  Go to UniProtKB:  P08603 | |||||
PHAROS:  P08603 GTEx:  ENSG00000000971  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P08603 | ||||
Sequence AnnotationsExpand | |||||
|
Entity ID: 2 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Complement regulator-acquiring surface protein 2 (CRASP-2) | 214 | Borreliella burgdorferi B31 | Mutation(s): 0  Gene Names: cspZ, BB_H06 | ||
UniProt | |||||
Find proteins for O50665 (Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)) Explore O50665  Go to UniProtKB:  O50665 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | O50665 | ||||
Sequence AnnotationsExpand | |||||
|
Ligands 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
MG Query on MG | E [auth B], F [auth C] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 43.742 | α = 90 |
b = 53.772 | β = 92.99 |
c = 116.587 | γ = 90 |
Software Name | Purpose |
---|---|
PHENIX | refinement |
HKL-2000 | data collection |
SCALEPACK | data scaling |
PHASER | phasing |
PDB_EXTRACT | data extraction |
Funding Organization | Location | Grant Number |
---|---|---|
National Institutes of Health/National Institute on Deafness and Other Communication Disorders (NIH/NIDCD) | United States | R01DC006917 |
National Institutes of Health/National Institute on Deafness and Other Communication Disorders (NIH/NIDCD) | United States | R21DC011066 |