Download MendeleyInsights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis
Liu, A., Yan, H., Wu, Y., Li, Y., Liu, J.To be published.
6ATG
Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis
- PDB DOI: https://doi.org/10.2210/pdb6ATG/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Homo sapiens, Borreliella burgdorferi B31
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2017-08-29 Released: 2018-09-12
- Funding Organization(s): National Institutes of Health/National Institute on Deafness and Other Communication Disorders (NIH/NIDCD)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 Å
- R-Value Free: 0.207
- R-Value Work: 0.178
- R-Value Observed: 0.179
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| HCG40889, isoform CRA_b | 61 | Homo sapiens | Mutation(s): 0 Gene Names: hCG_40889 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P08603 (Homo sapiens) Explore P08603 Go to UniProtKB: P08603 | |||||
PHAROS: P08603 GTEx: ENSG00000000971 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P08603 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Complement regulator-acquiring surface protein 2 (CRASP-2) | 214 | Borreliella burgdorferi B31 | Mutation(s): 0 Gene Names: cspZ, BB_H06 |  | |
UniProt | |||||
Find proteins for O50665 (Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)) Explore O50665 Go to UniProtKB: O50665 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O50665 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| MG Query on MG | E [auth B], F [auth C] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 Å
- R-Value Free: 0.207
- R-Value Work: 0.178
- R-Value Observed: 0.179
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 43.742 | α = 90 |
| b = 53.772 | β = 92.99 |
| c = 116.587 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-2000 | data collection |
| SCALEPACK | data scaling |
| PHASER | phasing |
| PDB_EXTRACT | data extraction |
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute on Deafness and Other Communication Disorders (NIH/NIDCD) | United States | R01DC006917 |
| National Institutes of Health/National Institute on Deafness and Other Communication Disorders (NIH/NIDCD) | United States | R21DC011066 |
Revision History (Full details and data files)
- Version 1.0: 2018-09-12
Type: Initial release - Version 1.1: 2019-02-20
Changes: Author supporting evidence, Data collection - Version 1.2: 2019-12-18
Changes: Author supporting evidence - Version 1.3: 2023-10-04
Changes: Data collection, Database references, Derived calculations, Refinement description
