5VNT

Solution NMR Structure of the C-terminal Headpiece Domain of Villin 4 from A.thaliana, the First Non-Vertebrate Headpiece Structure

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5vnta_	All alpha proteins	VHP, Villin headpiece domain	VHP, Villin headpiece domain	automated matches	automated matches	Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	VHP Villin headpiece domain	8067115	4000757	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	VHP Villin headpiece domain	8067116	3001263	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02209	e5vntA1	A: alpha arrays	X: VHP, Villin headpiece domain (From Topology)	H: VHP, Villin headpiece domain (From Topology)	T: VHP, Villin headpiece domain	F: PF02209	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.950.10	Mainly Alpha	Orthogonal Bundle	Villin Headpiece Domain	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF02209	Villin headpiece domain (VHP)	Villin headpiece domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Villin-4	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding cytoskeletal protein binding actin binding protein-containing complex binding protein binding actin filament binding	multicellular organismal process plant epidermal cell differentiation cellular developmental process developmental growth plant epidermis development cell development cell growth multicellular organism development root hair cell development cell differentiation anatomical structure development cell maturation root development trichoblast differentiation multicellular organismal process plant epidermal cell differentiation cellular developmental process developmental growth plant epidermis development cell development cell growth multicellular organism development root hair cell development cell differentiation anatomical structure development cell maturation root development trichoblast differentiation system development developmental process root hair elongation plant organ development developmental cell growth root morphogenesis root epidermal cell differentiation growth root hair cell differentiation developmental maturation tissue development developmental growth involved in morphogenesis plant organ morphogenesis anatomical structure morphogenesis trichoblast maturation anatomical structure maturation cellular process root system development regulation of cellular process regulation of cellular component size negative regulation of biological process protein-containing complex disassembly regulation of protein-containing complex disassembly actin filament depolymerization regulation of actin filament depolymerization cellular component biogenesis actin filament capping cellular component assembly actin filament-based process negative regulation of supramolecular fiber organization regulation of biological quality negative regulation of actin filament polymerization cellular component disassembly regulation of biological process negative regulation of cellular component organization actin filament organization regulation of organelle organization negative regulation of protein depolymerization negative regulation of protein-containing complex assembly regulation of protein polymerization regulation of supramolecular fiber organization supramolecular fiber organization regulation of cytoskeleton organization regulation of cellular component organization regulation of actin filament-based process cellular component organization regulation of protein-containing complex assembly negative regulation of protein-containing complex disassembly negative regulation of cellular process protein-containing complex assembly negative regulation of protein polymerization cellular component organization or biogenesis regulation of actin filament polymerization actin polymerization or depolymerization protein polymerization regulation of actin filament organization actin cytoskeleton organization actin filament polymerization protein-containing complex organization regulation of protein depolymerization negative regulation of cytoskeleton organization biological regulation regulation of actin polymerization or depolymerization regulation of cellular component biogenesis organelle organization negative regulation of organelle organization regulation of actin filament length regulation of actin cytoskeleton organization negative regulation of actin filament depolymerization protein depolymerization cytoskeleton organization regulation of anatomical structure size actin crosslink formation actin filament severing localization cellular localization transport establishment of localization in cell cytoplasmic streaming intracellular transport establishment of localization	intracellular organelle intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle cellular anatomical entity non-membrane-bounded organelle cytoplasm cytosol cell periphery plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR007123	Gelsolin-like domain	Domain
A	IPR029006	ADF-H/Gelsolin-like domain superfamily	Homologous Superfamily
A	IPR036886	Villin headpiece domain superfamily	Homologous Superfamily
A	IPR007122	Villin/Gelsolin	Family
A	IPR003128	Villin headpiece	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.