Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyRas-like P-loop GTPases8089854 3002022 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyRas-like P-loop GTPases8089854 3002022 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyRas-like P-loop GTPases8089854 3002022 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyRas-like P-loop GTPases8089854 3002022 SCOP2B (2022-06-29)
HSCOP2B SuperfamilySNARE-like8082715 3001113 SCOP2B (2022-06-29)
PSCOP2B SuperfamilySNARE-like8082715 3001113 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF00025e5a1xA1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00025ECOD (1.6)
BPF00025e5a1xB1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00025ECOD (1.6)
IPF00025e5a1xI1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00025ECOD (1.6)
JPF00025e5a1xJ1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00025ECOD (1.6)
CPF00400e5a1xC1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
CPF04053e5a1xC3 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF04053ECOD (1.6)
CPF04053e5a1xC2 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF04053ECOD (1.6)
KPF00400e5a1xK1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
KPF04053e5a1xK2 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF04053ECOD (1.6)
KPF04053e5a1xK3 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF04053ECOD (1.6)
DPF00400e5a1xD2 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
DPF04053e5a1xD1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF04053ECOD (1.6)
DPF04053e5a1xD3 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF04053ECOD (1.6)
LPF00400e5a1xL1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
LPF04053e5a1xL3 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF04053ECOD (1.6)
LPF04053e5a1xL2 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF04053ECOD (1.6)
EPF01602e5a1xE1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF01602ECOD (1.6)
MPF08752e5a1xM1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF08752ECOD (1.6)
MPF01602e5a1xM3 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF01602ECOD (1.6)
MPF16381e5a1xM2 A: a+b two layersX: TBP-likeH: Subdomain of clathrin and coatomer appendage domain (From Topology)T: Subdomain of clathrin and coatomer appendage domainF: PF16381ECOD (1.6)
FPF01217e5a1xF1 A: a+b three layersX: Profilin-likeH: profilin-like (From Topology)T: profilin-likeF: PF01217ECOD (1.6)
NPF01217e5a1xN1 A: a+b three layersX: Profilin-likeH: profilin-like (From Topology)T: profilin-likeF: PF01217ECOD (1.6)
GPF07718e5a1xG2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07718ECOD (1.6)
GPF01602e5a1xG4 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF01602ECOD (1.6)
GPF14806e5a1xG3 A: a+b two layersX: TBP-likeH: Subdomain of clathrin and coatomer appendage domain (From Topology)T: Subdomain of clathrin and coatomer appendage domainF: PF14806ECOD (1.6)
OPF07718e5a1xO3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07718ECOD (1.6)
OPF01602e5a1xO2 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF01602ECOD (1.6)
OPF14806e5a1xO1 A: a+b two layersX: TBP-likeH: Subdomain of clathrin and coatomer appendage domain (From Topology)T: Subdomain of clathrin and coatomer appendage domainF: PF14806ECOD (1.6)
HPF00928e5a1xH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Common fold of diphtheria toxin/transcription factors/cytochrome fF: PF00928ECOD (1.6)
HPF01217e5a1xH3 A: a+b three layersX: Profilin-likeH: profilin-like (From Topology)T: profilin-likeF: PF01217ECOD (1.6)
PPF00928e5a1xP1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Common fold of diphtheria toxin/transcription factors/cytochrome fF: PF00928ECOD (1.6)
PPF01217e5a1xP3 A: a+b three layersX: Profilin-likeH: profilin-like (From Topology)T: profilin-likeF: PF01217ECOD (1.6)
QPF00928e5a1xQ1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Common fold of diphtheria toxin/transcription factors/cytochrome fF: PF00928ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, I, J
PF00025ADP-ribosylation factor family (Arf)ADP-ribosylation factor familyPfam combines a number of different Prosite families togetherDomain
C, K
PF04053Coatomer WD associated region (Coatomer_WDAD)Coatomer WD associated region- Repeat
C, K
PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
D, L
PF04053Coatomer WD associated region (Coatomer_WDAD)Coatomer WD associated region- Repeat
D, L
PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
E, M
PF01602Adaptin N terminal region (Adaptin_N)Adaptin N terminal region- Repeat
E, M
PF16381Coatomer subunit gamma-1 C-terminal appendage platform (Coatomer_g_Cpla)Coatomer subunit gamma-1 C-terminal appendage platformCoatomer_g_Cpla is the very C-terminal domain of the eukaryotic Coatomer subunit gamma-1 proteins. It acts as a platform domain to the C-terminal appendage. It carries one single protein/protein interaction site, which is the binding site for ARFGAP2 ...Coatomer_g_Cpla is the very C-terminal domain of the eukaryotic Coatomer subunit gamma-1 proteins. It acts as a platform domain to the C-terminal appendage. It carries one single protein/protein interaction site, which is the binding site for ARFGAP2 or ADP-ribosylation factor GTPase-activating protein. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The gamma-COPI is part of one of two subcomplexes that make up the heptameric coatomer complex along with the beta, delta and zeta subunits [1].
Domain
E, M
PF08752Coatomer gamma subunit appendage platform subdomain (COP-gamma_platf)Coatomer gamma subunit appendage platform subdomainCOPI-coated vesicles function in retrograde transport from the Golgi to the ER, and in intra-Golgi transport. This is the platform subdomain of the coatomer gamma subunit appendage domain. It carries a protein-protein interaction site at U ...COPI-coated vesicles function in retrograde transport from the Golgi to the ER, and in intra-Golgi transport. This is the platform subdomain of the coatomer gamma subunit appendage domain. It carries a protein-protein interaction site at UniProt:P53620, residue W776, which in yeast binds to the ARFGAP Glo3p, and in mammalian gamma-COP binds to a Glo3p orthologue, ARFGAP2 [1].
Domain
F, N
PF01217Clathrin adaptor complex small chain (Clat_adaptor_s)Clathrin adaptor complex small chain- Domain
G, O
PF01602Adaptin N terminal region (Adaptin_N)Adaptin N terminal region- Repeat
G, O
PF14806Coatomer beta subunit appendage platform (Coatomer_b_Cpla)Coatomer beta subunit appendage platformThis family is found at the C-terminus of the coatamer beta subunit proteins (Beta-coat proteins). It is a platform domain on the appendage that carries a highly conserved tryptophan.Domain
H, P, Q
PF00928Adaptor complexes medium subunit family (Adap_comp_sub)Adaptor complexes medium subunit family- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, I, J
ADP-RIBOSYLATION FACTOR 1
C, K
COATOMER SUBUNIT ALPHA
D, L
COATOMER SUBUNIT BETA'
E, M
COATOMER SUBUNIT GAMMA-1
F, N
COATOMER SUBUNIT ZETA-1-
G, O
COATOMER SUBUNIT BETA
H, P, Q
COATOMER SUBUNIT DELTA-

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, I, J
IPR045872ADP-ribosylation factor 1-5Family
A, B, I, J
IPR005225Small GTP-binding protein domainDomain
A, B, I, J
IPR006689Small GTPase superfamily, ARF/SAR typeFamily
A, B, I, J
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
C, K
IPR019775WD40 repeat, conserved siteConserved Site
C, K
IPR016391Coatomer subunit alphaFamily
C, K
IPR010714Coatomer, alpha subunit, C-terminalDomain
C, K
IPR047312Coatomer subunit alpha, WD Associated RegionDomain
C, K
IPR011048Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamilyHomologous Superfamily
C, K
IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
C, K
IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
C, K
IPR006692Coatomer, WD associated regionDomain
C, K
IPR001680WD40 repeatRepeat
C, K
IPR020472G-protein beta WD-40 repeatRepeat
D, L
IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
D, L
IPR016453Coatomer beta' subunit (COPB2)Family
D, L
IPR006692Coatomer, WD associated regionDomain
D, L
IPR001680WD40 repeatRepeat
D, L
IPR020472G-protein beta WD-40 repeatRepeat
D, L
IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
E, M
IPR016024Armadillo-type foldHomologous Superfamily
E, M
IPR002553Clathrin/coatomer adaptor, adaptin-like, N-terminalDomain
E, M
IPR013040Coatomer, gamma subunit, appendage, Ig-like subdomainDomain
E, M
IPR013041Clathrin adaptor, appendage, Ig-like subdomain superfamilyHomologous Superfamily
E, M
IPR011989Armadillo-like helicalHomologous Superfamily
E, M
IPR032154Coatomer subunit gamma, C-terminalDomain
E, M
IPR017106Coatomer gamma subunitFamily
E, M
IPR037067Coatomer, gamma subunit, appendage domain superfamilyHomologous Superfamily
E, M
IPR012295TBP domain superfamilyHomologous Superfamily
E, M
IPR009028Coatomer/calthrin adaptor appendage, C-terminal subdomainHomologous Superfamily
F, N
IPR000804Clathrin adaptor complex, small chainConserved Site
F, N
IPR022775AP complex, mu/sigma subunitDomain
F, N
IPR039652Coatomer subunit zetaFamily
F, N
IPR011012Longin-like domain superfamilyHomologous Superfamily
G, O
IPR016460Coatomer beta subunit (COPB1)Family
G, O
IPR016024Armadillo-type foldHomologous Superfamily
G, O
IPR002553Clathrin/coatomer adaptor, adaptin-like, N-terminalDomain
G, O
IPR011710Coatomer beta subunit, C-terminalDomain
G, O
IPR029446Coatomer beta subunit, appendage platform domainDomain
G, O
IPR011989Armadillo-like helicalHomologous Superfamily
H, P, Q
IPR011012Longin-like domain superfamilyHomologous Superfamily
H, P, Q
IPR027059Coatomer delta subunitFamily
H, P, Q
IPR022775AP complex, mu/sigma subunitDomain
H, P, Q
IPR036168AP-2 complex subunit mu, C-terminal superfamilyHomologous Superfamily
H, P, Q
IPR028565Mu homology domainDomain