4BOG

The structure and super-organization of acetylcholine receptor-rapsyn complexes

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: PDBTM

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth 0]	Neur_chan_LBD	e4bog01	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
A [auth 0]	Neur_chan_memb	e4bog02	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
F [auth B]	Neur_chan_LBD	e4bogB4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
F [auth B]	Neur_chan_memb	e4bogB3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
K [auth G]	Neur_chan_LBD	e4bogG4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
K [auth G]	Neur_chan_memb	e4bogG3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
P [auth L]	Neur_chan_LBD	e4bogL4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
P [auth L]	Neur_chan_memb	e4bogL3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
U [auth Q]	Neur_chan_LBD	e4bogQ4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
U [auth Q]	Neur_chan_memb	e4bogQ3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
Z [auth V]	Neur_chan_LBD	e4bogV4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
Z [auth V]	Neur_chan_memb	e4bogV3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
AA [auth W]	Neur_chan_LBD	e4bogW5	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
AA [auth W]	Neur_chan_memb	e4bogW6	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
B [auth 1]	Neur_chan_LBD	e4bog15	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
B [auth 1]	Neur_chan_memb	e4bog16	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
G [auth C]	Neur_chan_LBD	e4bogC5	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
G [auth C]	Neur_chan_memb	e4bogC6	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
L [auth H]	Neur_chan_LBD	e4bogH5	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
L [auth H]	Neur_chan_memb	e4bogH6	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
Q [auth M]	Neur_chan_LBD	e4bogM5	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
Q [auth M]	Neur_chan_memb	e4bogM6	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
V [auth R]	Neur_chan_LBD	e4bogR5	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
V [auth R]	Neur_chan_memb	e4bogR6	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
BA [auth X]	Neur_chan_LBD	e4bogX2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
BA [auth X]	Neur_chan_memb	e4bogX1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
C [auth 2]	Neur_chan_LBD	e4bog21	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
C [auth 2]	Neur_chan_memb	e4bog22	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
DA [auth Z]	Neur_chan_LBD	e4bogZ2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
DA [auth Z]	Neur_chan_memb	e4bogZ1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
E [auth A]	Neur_chan_LBD	e4bogA2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
E [auth A]	Neur_chan_memb	e4bogA1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
H [auth D]	Neur_chan_LBD	e4bogD2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
H [auth D]	Neur_chan_memb	e4bogD1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
J [auth F]	Neur_chan_LBD	e4bogF2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
J [auth F]	Neur_chan_memb	e4bogF1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
M [auth I]	Neur_chan_LBD	e4bogI2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
M [auth I]	Neur_chan_memb	e4bogI1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
O [auth K]	Neur_chan_LBD	e4bogK2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
O [auth K]	Neur_chan_memb	e4bogK1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
R [auth N]	Neur_chan_LBD	e4bogN2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
R [auth N]	Neur_chan_memb	e4bogN1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
T [auth P]	Neur_chan_LBD	e4bogP2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
T [auth P]	Neur_chan_memb	e4bogP1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
W [auth S]	Neur_chan_LBD	e4bogS2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
W [auth S]	Neur_chan_memb	e4bogS1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
Y [auth U]	Neur_chan_LBD	e4bogU2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
Y [auth U]	Neur_chan_memb	e4bogU1	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
CA [auth Y]	Neur_chan_LBD	e4bogY4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
CA [auth Y]	Neur_chan_memb	e4bogY3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
D [auth 3]	Neur_chan_LBD	e4bog34	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
D [auth 3]	Neur_chan_memb	e4bog33	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
I [auth E]	Neur_chan_LBD	e4bogE4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
I [auth E]	Neur_chan_memb	e4bogE3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
N [auth J]	Neur_chan_LBD	e4bogJ4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
N [auth J]	Neur_chan_memb	e4bogJ3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
S [auth O]	Neur_chan_LBD	e4bogO4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
S [auth O]	Neur_chan_memb	e4bogO3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)
X [auth T]	Neur_chan_LBD	e4bogT4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Nicotinic receptor ligand binding domain-like (From Topology)	T: Nicotinic receptor ligand binding domain-like	F: Neur_chan_LBD	ECOD (1.6)
X [auth T]	Neur_chan_memb	e4bogT3	A: alpha bundles	X: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)	T: Neurotransmitter-gated ion-channel transmembrane pore	F: Neur_chan_memb	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	PF02932	Neurotransmitter-gated ion-channel transmembrane region (Neur_chan_memb)	Neurotransmitter-gated ion-channel transmembrane region	-	Family
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	PF02931	Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)	Neurotransmitter-gated ion-channel ligand binding domain	-	Family
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	PF02932	Neurotransmitter-gated ion-channel transmembrane region (Neur_chan_memb)	Neurotransmitter-gated ion-channel transmembrane region	-	Family
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	PF02931	Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)	Neurotransmitter-gated ion-channel ligand binding domain	-	Family
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	PF02932	Neurotransmitter-gated ion-channel transmembrane region (Neur_chan_memb)	Neurotransmitter-gated ion-channel transmembrane region	-	Family
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	PF02931	Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)	Neurotransmitter-gated ion-channel ligand binding domain	-	Family
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	PF02932	Neurotransmitter-gated ion-channel transmembrane region (Neur_chan_memb)	Neurotransmitter-gated ion-channel transmembrane region	-	Family
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	PF02931	Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)	Neurotransmitter-gated ion-channel ligand binding domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	Acetylcholine receptor beta subunit	transmitter-gated monoatomic ion channel activity monoatomic cation transmembrane transporter activity molecular transducer activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity ligand-gated channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity acetylcholine-gated monoatomic cation-selective channel activity transporter activity ligand-gated monoatomic cation channel activity gated channel activity signaling receptor activity transmitter-gated monoatomic ion channel activity monoatomic cation transmembrane transporter activity molecular transducer activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity ligand-gated channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity acetylcholine-gated monoatomic cation-selective channel activity transporter activity ligand-gated monoatomic cation channel activity gated channel activity signaling receptor activity excitatory extracellular ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity monoatomic cation channel activity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential channel activity monoatomic ion transmembrane transporter activity transmitter-gated channel activity transmembrane transporter activity transmembrane signaling receptor activity	cellular response to nitrogen compound cellular response to stimulus cellular response to acetylcholine response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cell-cell signaling response to nitrogen compound acetylcholine receptor signaling pathway postsynaptic signal transduction cellular response to oxygen-containing compound cellular response to nitrogen compound cellular response to stimulus cellular response to acetylcholine response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cell-cell signaling response to nitrogen compound acetylcholine receptor signaling pathway postsynaptic signal transduction cellular response to oxygen-containing compound cell communication cellular response to chemical stimulus synaptic signaling response to chemical response to acetylcholine cellular process signal transduction	cell periphery postsynapse postsynaptic membrane synapse cell junction membrane plasma membrane plasma membrane region cellular anatomical entity synaptic membrane protein-containing complex plasma membrane protein complex membrane protein complex transporter complex cell periphery postsynapse postsynaptic membrane synapse cell junction membrane plasma membrane plasma membrane region cellular anatomical entity synaptic membrane protein-containing complex plasma membrane protein complex membrane protein complex transporter complex receptor complex acetylcholine-gated channel complex transmembrane transporter complex plasma membrane signaling receptor complex monoatomic ion channel complex
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	Acetylcholine receptor delta subunit	transmitter-gated monoatomic ion channel activity monoatomic cation transmembrane transporter activity molecular transducer activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity ligand-gated channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity acetylcholine-gated monoatomic cation-selective channel activity transporter activity ligand-gated monoatomic cation channel activity gated channel activity signaling receptor activity transmitter-gated monoatomic ion channel activity monoatomic cation transmembrane transporter activity molecular transducer activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity ligand-gated channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity acetylcholine-gated monoatomic cation-selective channel activity transporter activity ligand-gated monoatomic cation channel activity gated channel activity signaling receptor activity excitatory extracellular ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity monoatomic cation channel activity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential channel activity monoatomic ion transmembrane transporter activity transmitter-gated channel activity transmembrane transporter activity transmembrane signaling receptor activity	cellular response to nitrogen compound cellular response to stimulus cellular response to acetylcholine response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cell-cell signaling response to nitrogen compound acetylcholine receptor signaling pathway postsynaptic signal transduction cellular response to oxygen-containing compound cellular response to nitrogen compound cellular response to stimulus cellular response to acetylcholine response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cell-cell signaling response to nitrogen compound acetylcholine receptor signaling pathway postsynaptic signal transduction cellular response to oxygen-containing compound cell communication cellular response to chemical stimulus synaptic signaling response to chemical response to acetylcholine cellular process signal transduction	cell periphery postsynapse postsynaptic membrane synapse cell junction membrane plasma membrane plasma membrane region cellular anatomical entity synaptic membrane protein-containing complex plasma membrane protein complex membrane protein complex transporter complex cell periphery postsynapse postsynaptic membrane synapse cell junction membrane plasma membrane plasma membrane region cellular anatomical entity synaptic membrane protein-containing complex plasma membrane protein complex membrane protein complex transporter complex receptor complex acetylcholine-gated channel complex transmembrane transporter complex plasma membrane signaling receptor complex monoatomic ion channel complex
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	Acetylcholine receptor subunit alpha	transmitter-gated monoatomic ion channel activity monoatomic cation transmembrane transporter activity molecular transducer activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity ligand-gated channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity acetylcholine-gated monoatomic cation-selective channel activity transporter activity ligand-gated monoatomic cation channel activity gated channel activity signaling receptor activity transmitter-gated monoatomic ion channel activity monoatomic cation transmembrane transporter activity molecular transducer activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity ligand-gated channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity acetylcholine-gated monoatomic cation-selective channel activity transporter activity ligand-gated monoatomic cation channel activity gated channel activity signaling receptor activity excitatory extracellular ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity monoatomic cation channel activity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential channel activity monoatomic ion transmembrane transporter activity transmitter-gated channel activity transmembrane transporter activity transmembrane signaling receptor activity	-	cell periphery postsynapse postsynaptic membrane synapse cell junction membrane plasma membrane plasma membrane region cellular anatomical entity synaptic membrane
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	Acetylcholine receptor gamma subunit	transmitter-gated monoatomic ion channel activity monoatomic cation transmembrane transporter activity molecular transducer activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity ligand-gated channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity acetylcholine-gated monoatomic cation-selective channel activity transporter activity ligand-gated monoatomic cation channel activity gated channel activity signaling receptor activity transmitter-gated monoatomic ion channel activity monoatomic cation transmembrane transporter activity molecular transducer activity monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity ligand-gated channel activity postsynaptic neurotransmitter receptor activity passive transmembrane transporter activity acetylcholine-gated monoatomic cation-selective channel activity transporter activity ligand-gated monoatomic cation channel activity gated channel activity signaling receptor activity excitatory extracellular ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity extracellular ligand-gated monoatomic ion channel activity monoatomic cation channel activity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential channel activity monoatomic ion transmembrane transporter activity transmitter-gated channel activity transmembrane transporter activity transmembrane signaling receptor activity	cellular response to nitrogen compound cellular response to stimulus cellular response to acetylcholine response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cell-cell signaling response to nitrogen compound acetylcholine receptor signaling pathway postsynaptic signal transduction cellular response to oxygen-containing compound cellular response to nitrogen compound cellular response to stimulus cellular response to acetylcholine response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cell-cell signaling response to nitrogen compound acetylcholine receptor signaling pathway postsynaptic signal transduction cellular response to oxygen-containing compound cell communication cellular response to chemical stimulus synaptic signaling response to chemical response to acetylcholine cellular process signal transduction	cell periphery postsynapse postsynaptic membrane synapse cell junction membrane plasma membrane plasma membrane region cellular anatomical entity synaptic membrane protein-containing complex plasma membrane protein complex membrane protein complex transporter complex cell periphery postsynapse postsynaptic membrane synapse cell junction membrane plasma membrane plasma membrane region cellular anatomical entity synaptic membrane protein-containing complex plasma membrane protein complex membrane protein complex transporter complex receptor complex acetylcholine-gated channel complex transmembrane transporter complex plasma membrane signaling receptor complex monoatomic ion channel complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	IPR018000	Neurotransmitter-gated ion-channel, conserved site	Conserved Site
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	IPR038050	Neuronal acetylcholine receptor	Homologous Superfamily
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	Domain
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	IPR036719	Neurotransmitter-gated ion-channel transmembrane domain superfamily	Homologous Superfamily
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	IPR002394	Nicotinic acetylcholine receptor	Family
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	Domain
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Homologous Superfamily
A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], A [auth 0], F [auth B], K [auth G], P [auth L], U [auth Q], Z [auth V]	IPR006201	Neurotransmitter-gated ion-channel	Family
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	IPR018000	Neurotransmitter-gated ion-channel, conserved site	Conserved Site
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	IPR038050	Neuronal acetylcholine receptor	Homologous Superfamily
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	Domain
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	IPR036719	Neurotransmitter-gated ion-channel transmembrane domain superfamily	Homologous Superfamily
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	IPR002394	Nicotinic acetylcholine receptor	Family
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	Domain
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Homologous Superfamily
AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], AA [auth W], B [auth 1], G [auth C], L [auth H], Q [auth M], V [auth R]	IPR006201	Neurotransmitter-gated ion-channel	Family
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	IPR002394	Nicotinic acetylcholine receptor	Family
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	Domain
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	IPR018000	Neurotransmitter-gated ion-channel, conserved site	Conserved Site
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	IPR038050	Neuronal acetylcholine receptor	Homologous Superfamily
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	Domain
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	IPR036719	Neurotransmitter-gated ion-channel transmembrane domain superfamily	Homologous Superfamily
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Homologous Superfamily
BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], BA [auth X], C [auth 2], DA [auth Z], E [auth A], H [auth D], J [auth F], M [auth I], O [auth K], R [auth N], T [auth P], W [auth S], Y [auth U]	IPR006201	Neurotransmitter-gated ion-channel	Family
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	IPR018000	Neurotransmitter-gated ion-channel, conserved site	Conserved Site
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	IPR038050	Neuronal acetylcholine receptor	Homologous Superfamily
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	Domain
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	IPR036719	Neurotransmitter-gated ion-channel transmembrane domain superfamily	Homologous Superfamily
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	IPR002394	Nicotinic acetylcholine receptor	Family
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	Domain
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily	Homologous Superfamily
CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], CA [auth Y], D [auth 3], I [auth E], N [auth J], S [auth O], X [auth T]	IPR006201	Neurotransmitter-gated ion-channel	Family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A [auth 0], AA [auth W], B [auth 1], BA [auth X], C [auth 2] A [auth 0], AA [auth W], B [auth 1], BA [auth X], C [auth 2], CA [auth Y], D [auth 3], DA [auth Z], E [auth A], F [auth B], G [auth C], H [auth D], I [auth E], J [auth F], K [auth G], L [auth H], M [auth I], N [auth J], O [auth K], P [auth L], Q [auth M], R [auth N], S [auth O], T [auth P], U [auth Q], V [auth R], W [auth S], X [auth T], Y [auth U], Z [auth V]	PDBTM	Annotated as membrane protein by PDBTM