4A9G

Symmetrized cryo-EM reconstruction of E. coli DegQ 24-mer in complex with beta-casein

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
R	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
S	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
U	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
O	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
P	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
Q	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
T	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
V	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
W	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)
X [auth Y]	SCOP2B Superfamily	Trypsin-like serine proteases	8073980	3000114	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Trypsin_2	e4a9gA3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
A	PDZ_2	e4a9gA2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
A	PDZ_2,Trypsin_2	e4a9gA1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
C	Trypsin_2	e4a9gC3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
C	PDZ_2	e4a9gC2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
C	PDZ_2,Trypsin_2	e4a9gC1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
E	Trypsin_2	e4a9gE3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
E	PDZ_2	e4a9gE2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
E	PDZ_2,Trypsin_2	e4a9gE1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
G	Trypsin_2	e4a9gG3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
G	PDZ_2	e4a9gG2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
G	PDZ_2,Trypsin_2	e4a9gG1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
L	Trypsin_2	e4a9gL3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
L	PDZ_2	e4a9gL2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
L	PDZ_2,Trypsin_2	e4a9gL1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
N	Trypsin_2	e4a9gN3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
N	PDZ_2	e4a9gN2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
N	PDZ_2,Trypsin_2	e4a9gN1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
R	Trypsin_2	e4a9gR3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
R	PDZ_2	e4a9gR2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
R	PDZ_2,Trypsin_2	e4a9gR1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
S	Trypsin_2	e4a9gS3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
S	PDZ_2	e4a9gS2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
S	PDZ_2,Trypsin_2	e4a9gS1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
U	Trypsin_2	e4a9gU3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
U	PDZ_2	e4a9gU2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
U	PDZ_2,Trypsin_2	e4a9gU1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
B	Trypsin_2	e4a9gB3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
B	PDZ_2	e4a9gB2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
B	PDZ_2,Trypsin_2	e4a9gB1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
D	Trypsin_2	e4a9gD3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
D	PDZ_2	e4a9gD2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
D	PDZ_2,Trypsin_2	e4a9gD1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
F	Trypsin_2	e4a9gF3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
F	PDZ_2	e4a9gF2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
F	PDZ_2,Trypsin_2	e4a9gF1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
H	Trypsin_2	e4a9gH3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
H	PDZ_2	e4a9gH2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
H	PDZ_2,Trypsin_2	e4a9gH1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
I	Trypsin_2	e4a9gI3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
I	PDZ_2	e4a9gI2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
I	PDZ_2,Trypsin_2	e4a9gI1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
J	Trypsin_2	e4a9gJ3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
J	PDZ_2	e4a9gJ2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
J	PDZ_2,Trypsin_2	e4a9gJ1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
K	Trypsin_2	e4a9gK3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
K	PDZ_2	e4a9gK2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
K	PDZ_2,Trypsin_2	e4a9gK1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
M	Trypsin_2	e4a9gM3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
M	PDZ_2	e4a9gM2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
M	PDZ_2,Trypsin_2	e4a9gM1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
O	Trypsin_2	e4a9gO3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
O	PDZ_2	e4a9gO2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
O	PDZ_2,Trypsin_2	e4a9gO1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
P	Trypsin_2	e4a9gP3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
P	PDZ_2	e4a9gP2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
P	PDZ_2,Trypsin_2	e4a9gP1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
Q	Trypsin_2	e4a9gQ3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
Q	PDZ_2	e4a9gQ2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
Q	PDZ_2,Trypsin_2	e4a9gQ1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
T	Trypsin_2	e4a9gT3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
T	PDZ_2	e4a9gT2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
T	PDZ_2,Trypsin_2	e4a9gT1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
V	Trypsin_2	e4a9gV3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
V	PDZ_2	e4a9gV2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
V	PDZ_2,Trypsin_2	e4a9gV1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
W	Trypsin_2	e4a9gW3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
W	PDZ_2	e4a9gW2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
W	PDZ_2,Trypsin_2	e4a9gW1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)
X [auth Y]	Trypsin_2	e4a9gY3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel 2	F: Trypsin_2	ECOD (1.6)
X [auth Y]	PDZ_2	e4a9gY2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2	ECOD (1.6)
X [auth Y]	PDZ_2,Trypsin_2	e4a9gY1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PDZ_2,Trypsin_2	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X [auth Y]	PF13365	Trypsin-like peptidase domain (Trypsin_2)	Trypsin-like peptidase domain	This family includes trypsin-like peptidase domains.	Domain
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X [auth Y]	PF00595	PDZ domain (PDZ)	PDZ domain	PDZ domains are found in diverse signaling proteins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X [auth Y]	PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ	peptidase activity catalytic activity, acting on a protein serine hydrolase activity serine-type peptidase activity hydrolase activity serine-type endopeptidase activity catalytic activity endopeptidase activity identical protein binding protein binding binding	organonitrogen compound catabolic process organonitrogen compound metabolic process catabolic process proteolysis involved in protein catabolic process primary metabolic process protein catabolic process macromolecule catabolic process organic substance metabolic process proteolysis metabolic process protein metabolic process macromolecule metabolic process organic substance catabolic process protein quality control for misfolded or incompletely synthesized proteins	periplasmic space cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X [auth Y]	IPR009003	Peptidase S1, PA clan	Homologous Superfamily
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X [auth Y]	IPR011782	Peptidase S1C, Do	Family
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X [auth Y]	IPR001478	PDZ domain	Domain
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X [auth Y]	IPR001940	Peptidase S1C	Family
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X [auth Y]	IPR036034	PDZ superfamily	Homologous Superfamily