Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AMutL_C_Ce3ncvA2 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: DNA mismatch repair protein MutL regulatory subdomain (From Topology)T: DNA mismatch repair protein MutL regulatory subdomainF: MutL_C_CECOD (1.6)
AMutL_C_Ne3ncvA1 A: a+b two layersX: DNA mismatch repair protein MutL dimerization subdomain (From Topology)H: DNA mismatch repair protein MutL dimerization subdomain (From Topology)T: DNA mismatch repair protein MutL dimerization subdomainF: MutL_C_NECOD (1.6)
BMutL_C_Ce3ncvB2 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: DNA mismatch repair protein MutL regulatory subdomain (From Topology)T: DNA mismatch repair protein MutL regulatory subdomainF: MutL_C_CECOD (1.6)
BMutL_C_Ne3ncvB1 A: a+b two layersX: DNA mismatch repair protein MutL dimerization subdomain (From Topology)H: DNA mismatch repair protein MutL dimerization subdomain (From Topology)T: DNA mismatch repair protein MutL dimerization subdomainF: MutL_C_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF08676MutL C terminal dimerisation domain (MutL_C)MutL C terminal dimerisation domainMutL and MutS are key components of the DNA repair machinery that corrects replication errors [1]. MutS recognises mispaired or unpaired bases in a DNA duplex and in the presence of ATP, recruits MutL to form a DNA signaling complex for repair. The ...MutL and MutS are key components of the DNA repair machinery that corrects replication errors [1]. MutS recognises mispaired or unpaired bases in a DNA duplex and in the presence of ATP, recruits MutL to form a DNA signaling complex for repair. The N terminal region of MutL contains the ATPase domain and the C terminal is involved in dimerisation [3].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
DNA mismatch repair protein mutL