3IYG

Ca model of bovine TRiC/CCT derived from a 4.0 Angstrom cryo-EM map

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth Q]	Cpn60_TCP1_1st	e3iygQ1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
A [auth Q]	Cpn60_TCP1_2nd	e3iygQ3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
A [auth Q]	Cpn60_TCP1_3rd	e3iygQ2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
B [auth G]	Cpn60_TCP1_1st	e3iygG1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
B [auth G]	Cpn60_TCP1_2nd	e3iygG3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
B [auth G]	Cpn60_TCP1_2nd_1	e3iygG2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
C [auth Z]	Cpn60_TCP1_1st	e3iygZ1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
C [auth Z]	Cpn60_TCP1_2nd	e3iygZ3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
C [auth Z]	Cpn60_TCP1_2nd_1	e3iygZ2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
D	Cpn60_TCP1_1st	e3iygD2	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
D	Cpn60_TCP1_2nd	e3iygD1	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
D	Cpn60_TCP1_2nd_1	e3iygD3	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
E [auth B]	Cpn60_TCP1_1st	e3iygB1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
E [auth B]	Cpn60_TCP1_2nd	e3iygB2	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
E [auth B]	Cpn60_TCP1_2nd_1	e3iygB3	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
F [auth E]	Cpn60_TCP1_1st	e3iygE1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
F [auth E]	Cpn60_TCP1_2nd	e3iygE3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
F [auth E]	Cpn60_TCP1_2nd_1	e3iygE2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
G [auth A]	Cpn60_TCP1_1st	e3iygA1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
G [auth A]	Cpn60_TCP1_2nd	e3iygA3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
G [auth A]	Cpn60_TCP1_2nd_1	e3iygA2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)
H	Cpn60_TCP1_1st	e3iygH1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
H	Cpn60_TCP1_2nd	e3iygH3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd	ECOD (1.6)
H	Cpn60_TCP1_2nd_1	e3iygH2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_2nd_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth Q]	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family
B [auth G]	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family
C [auth Z]	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family
D	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family
E [auth B]	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family
G [auth A]	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family
H	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth Q]	T-complex protein 1 subunit theta	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle cell projection organelle cilium cellular anatomical entity plasma membrane bounded cell projection protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cytosol chaperonin-containing T-complex intracellular protein-containing complex intracellular organelle membrane-bounded organelle cell projection organelle cilium cellular anatomical entity plasma membrane bounded cell projection protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cytosol chaperonin-containing T-complex intracellular protein-containing complex intracellular organelle centrosome microtubule organizing center cytoskeleton intracellular non-membrane-bounded organelle microtubule cytoskeleton non-membrane-bounded organelle
B [auth G]	T-complex protein 1 subunit gamma	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone	protein localization establishment of protein localization to telomere regulation of localization establishment of protein localization cellular localization regulation of cellular process regulation of protein localization positive regulation of protein localization to chromosome, telomeric region positive regulation of biological process positive regulation of establishment of protein localization positive regulation of establishment of protein localization to telomere localization regulation of protein localization to chromosome, telomeric region cellular macromolecule localization protein localization establishment of protein localization to telomere regulation of localization establishment of protein localization cellular localization regulation of cellular process regulation of protein localization positive regulation of protein localization to chromosome, telomeric region positive regulation of biological process positive regulation of establishment of protein localization positive regulation of establishment of protein localization to telomere localization regulation of protein localization to chromosome, telomeric region cellular macromolecule localization establishment of protein localization to chromosome positive regulation of cellular process regulation of establishment of protein localization to chromosome regulation of biological process biological regulation regulation of establishment of protein localization protein localization to chromosome, telomeric region establishment of localization establishment of protein localization to organelle protein localization to chromosome regulation of cellular localization macromolecule localization protein localization to organelle regulation of establishment of protein localization to telomere positive regulation of protein localization cellular process regulation of protein stability regulation of biological quality protein stabilization positive regulation of organelle organization telomere organization regulation of DNA biosynthetic process positive regulation of macromolecule biosynthetic process RNA-templated DNA biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process telomere maintenance via telomere lengthening positive regulation of metabolic process organic substance biosynthetic process positive regulation of telomere maintenance via telomere lengthening positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of telomere maintenance positive regulation of nucleobase-containing compound metabolic process cellular metabolic process primary metabolic process regulation of cellular metabolic process DNA metabolic process regulation of chromosome organization regulation of telomere maintenance via telomere lengthening regulation of organelle organization positive regulation of chromosome organization telomere maintenance organic cyclic compound metabolic process biosynthetic process positive regulation of DNA metabolic process positive regulation of telomere maintenance via telomerase organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process DNA biosynthetic process regulation of metabolic process regulation of DNA metabolic process regulation of telomere maintenance regulation of cellular component organization positive regulation of cellular component organization cellular biosynthetic process positive regulation of cellular metabolic process cellular component organization nucleic acid biosynthetic process organic substance metabolic process positive regulation of biosynthetic process cellular component organization or biogenesis regulation of biosynthetic process telomere maintenance via telomerase chromosome organization positive regulation of DNA biosynthetic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process regulation of telomere maintenance via telomerase regulation of cellular biosynthetic process organelle organization positive regulation of cellular biosynthetic process organonitrogen compound metabolic process gene expression protein maturation protein folding protein metabolic process chaperone-mediated protein folding sperm-egg recognition sexual reproduction cell-cell recognition reproductive process fertilization binding of sperm to zona pellucida cell recognition single fertilization	protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex zona pellucida receptor complex cell body polymeric cytoskeletal fiber intracellular organelle cytoskeleton organelle protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex zona pellucida receptor complex cell body polymeric cytoskeletal fiber intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle supramolecular fiber microtubule supramolecular polymer supramolecular complex microtubule cytoskeleton non-membrane-bounded organelle
C [auth Z]	T-complex protein 1 subunit zeta	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex
D	T-complex protein 1 subunit delta	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle cell projection organelle cilium cellular anatomical entity plasma membrane bounded cell projection intracellular anatomical structure pigment granule intracellular vesicle intracellular membrane-bounded organelle intracellular organelle melanosome cytoplasmic vesicle cytoplasm membrane-bounded organelle cell projection organelle cilium cellular anatomical entity plasma membrane bounded cell projection intracellular anatomical structure pigment granule intracellular vesicle intracellular membrane-bounded organelle intracellular organelle melanosome cytoplasmic vesicle cytoplasm vesicle protein-containing complex protein folding chaperone complex cytosol chaperonin-containing T-complex intracellular protein-containing complex centrosome microtubule organizing center cytoskeleton intracellular non-membrane-bounded organelle microtubule cytoskeleton non-membrane-bounded organelle
E [auth B]	T-complex protein 1 subunit beta	ATP-dependent protein folding chaperone protein folding chaperone ATP-dependent activity binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP-dependent protein folding chaperone protein folding chaperone ATP-dependent activity binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ubiquitin protein ligase binding ubiquitin-like protein ligase binding enzyme binding	RNA localization to nucleus regulation of localization regulation of biological process biological regulation positive regulation of biological process positive regulation of telomerase RNA localization to Cajal body telomerase RNA localization to Cajal body regulation of telomerase RNA localization to Cajal body localization telomerase RNA localization macromolecule localization RNA localization to Cajal body RNA localization protein localization RNA localization to nucleus regulation of localization regulation of biological process biological regulation positive regulation of biological process positive regulation of telomerase RNA localization to Cajal body telomerase RNA localization to Cajal body regulation of telomerase RNA localization to Cajal body localization telomerase RNA localization macromolecule localization RNA localization to Cajal body RNA localization protein localization establishment of protein localization to telomere establishment of protein localization cellular localization regulation of cellular process regulation of protein localization positive regulation of protein localization to chromosome, telomeric region positive regulation of establishment of protein localization positive regulation of establishment of protein localization to telomere regulation of protein localization to chromosome, telomeric region cellular macromolecule localization establishment of protein localization to chromosome positive regulation of cellular process regulation of establishment of protein localization to chromosome regulation of establishment of protein localization protein localization to chromosome, telomeric region establishment of localization establishment of protein localization to organelle protein localization to chromosome regulation of cellular localization protein localization to organelle regulation of establishment of protein localization to telomere positive regulation of protein localization cellular process regulation of protein stability regulation of biological quality protein stabilization cellular component organization cellular component biogenesis cellular component assembly chaperone-mediated protein complex assembly protein-containing complex organization protein-containing complex assembly cellular component organization or biogenesis organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process protein metabolic process macromolecule metabolic process scaRNA localization to Cajal body positive regulation of organelle organization telomere organization regulation of DNA biosynthetic process positive regulation of macromolecule biosynthetic process RNA-templated DNA biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process telomere maintenance via telomere lengthening positive regulation of metabolic process positive regulation of telomere maintenance via telomere lengthening positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of telomere maintenance positive regulation of nucleobase-containing compound metabolic process regulation of cellular metabolic process DNA metabolic process regulation of chromosome organization regulation of telomere maintenance via telomere lengthening regulation of organelle organization positive regulation of chromosome organization telomere maintenance organic cyclic compound metabolic process positive regulation of DNA metabolic process positive regulation of telomere maintenance via telomerase organic cyclic compound biosynthetic process regulation of macromolecule biosynthetic process DNA biosynthetic process regulation of metabolic process regulation of DNA metabolic process regulation of telomere maintenance regulation of cellular component organization positive regulation of cellular component organization positive regulation of cellular metabolic process nucleic acid biosynthetic process positive regulation of biosynthetic process regulation of biosynthetic process telomere maintenance via telomerase chromosome organization positive regulation of DNA biosynthetic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process nucleic acid metabolic process regulation of telomere maintenance via telomerase regulation of cellular biosynthetic process organelle organization positive regulation of cellular biosynthetic process sperm-egg recognition sexual reproduction cell-cell recognition reproductive process fertilization binding of sperm to zona pellucida cell recognition single fertilization chaperone-mediated protein folding chaperone mediated protein folding independent of cofactor 'de novo' protein folding 'de novo' post-translational protein folding	protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex zona pellucida receptor complex cell body polymeric cytoskeletal fiber intracellular organelle cytoskeleton organelle protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex zona pellucida receptor complex cell body polymeric cytoskeletal fiber intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle supramolecular fiber microtubule supramolecular polymer supramolecular complex microtubule cytoskeleton non-membrane-bounded organelle
F [auth E]	T-complex protein 1 subunit	-	-	-
G [auth A]	T-complex protein 1 subunit alpha	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex intracellular organelle centrosome microtubule organizing center cytoskeleton organelle intracellular non-membrane-bounded organelle protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex intracellular organelle centrosome microtubule organizing center cytoskeleton organelle intracellular non-membrane-bounded organelle microtubule cytoskeleton non-membrane-bounded organelle
H	T-complex protein 1 subunit eta	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone	protein localization establishment of protein localization to telomere regulation of localization establishment of protein localization cellular localization regulation of cellular process regulation of protein localization positive regulation of protein localization to chromosome, telomeric region positive regulation of biological process positive regulation of establishment of protein localization positive regulation of establishment of protein localization to telomere localization regulation of protein localization to chromosome, telomeric region cellular macromolecule localization protein localization establishment of protein localization to telomere regulation of localization establishment of protein localization cellular localization regulation of cellular process regulation of protein localization positive regulation of protein localization to chromosome, telomeric region positive regulation of biological process positive regulation of establishment of protein localization positive regulation of establishment of protein localization to telomere localization regulation of protein localization to chromosome, telomeric region cellular macromolecule localization establishment of protein localization to chromosome positive regulation of cellular process regulation of establishment of protein localization to chromosome regulation of biological process biological regulation regulation of establishment of protein localization protein localization to chromosome, telomeric region establishment of localization establishment of protein localization to organelle protein localization to chromosome regulation of cellular localization macromolecule localization protein localization to organelle regulation of establishment of protein localization to telomere positive regulation of protein localization cellular process regulation of protein stability regulation of biological quality protein stabilization positive regulation of organelle organization telomere organization regulation of DNA biosynthetic process positive regulation of macromolecule biosynthetic process RNA-templated DNA biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process telomere maintenance via telomere lengthening positive regulation of metabolic process organic substance biosynthetic process positive regulation of telomere maintenance via telomere lengthening positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of telomere maintenance positive regulation of nucleobase-containing compound metabolic process cellular metabolic process primary metabolic process regulation of cellular metabolic process DNA metabolic process regulation of chromosome organization regulation of telomere maintenance via telomere lengthening regulation of organelle organization positive regulation of chromosome organization telomere maintenance organic cyclic compound metabolic process biosynthetic process positive regulation of DNA metabolic process positive regulation of telomere maintenance via telomerase organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process DNA biosynthetic process regulation of metabolic process regulation of DNA metabolic process regulation of telomere maintenance regulation of cellular component organization positive regulation of cellular component organization cellular biosynthetic process positive regulation of cellular metabolic process cellular component organization nucleic acid biosynthetic process organic substance metabolic process positive regulation of biosynthetic process cellular component organization or biogenesis regulation of biosynthetic process telomere maintenance via telomerase chromosome organization positive regulation of DNA biosynthetic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process regulation of telomere maintenance via telomerase regulation of cellular biosynthetic process organelle organization positive regulation of cellular biosynthetic process organonitrogen compound metabolic process gene expression protein maturation protein folding protein metabolic process chaperone-mediated protein folding sperm-egg recognition sexual reproduction cell-cell recognition reproductive process fertilization binding of sperm to zona pellucida cell recognition single fertilization	protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex cell body polymeric cytoskeletal fiber intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle protein-containing complex intracellular anatomical structure protein folding chaperone complex cytoplasm cellular anatomical entity cytosol chaperonin-containing T-complex intracellular protein-containing complex cell body polymeric cytoskeletal fiber intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle supramolecular fiber microtubule supramolecular polymer supramolecular complex microtubule cytoskeleton non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth Q]	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
A [auth Q]	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
A [auth Q]	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
A [auth Q]	IPR012721	T-complex protein 1, theta subunit	Family
A [auth Q]	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
A [auth Q]	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
A [auth Q]	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family
B [auth G]	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
B [auth G]	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
B [auth G]	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
B [auth G]	IPR012719	T-complex protein 1, gamma subunit	Family
B [auth G]	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
B [auth G]	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
B [auth G]	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family
C [auth Z]	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
C [auth Z]	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
C [auth Z]	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
C [auth Z]	IPR012722	T-complex protein 1, zeta subunit	Family
C [auth Z]	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
C [auth Z]	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
C [auth Z]	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family
D	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
D	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
D	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
D	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
D	IPR012717	T-complex protein 1, delta subunit	Family
D	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
D	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family
E [auth B]	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
E [auth B]	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
E [auth B]	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
E [auth B]	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
E [auth B]	IPR012716	T-complex protein 1, beta subunit	Family
E [auth B]	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
E [auth B]	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family
G [auth A]	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
G [auth A]	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
G [auth A]	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
G [auth A]	IPR012715	T-complex protein 1, alpha subunit	Family
G [auth A]	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
G [auth A]	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
G [auth A]	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family
H	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
H	IPR012720	T-complex protein 1, eta subunit	Family
H	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)	Family
H	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
H	IPR002194	Chaperonin TCP-1, conserved site	Conserved Site
H	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
H	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.

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3IYG

Ca model of bovine TRiC/CCT derived from a 4.0 Angstrom cryo-EM map

External Resource: Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Protein Family Annotation Pfam Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage