Annotations: 6U7J

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6u7ja2	All beta proteins	Immunoglobulin-like beta-sandwich	beta-Galactosidase/glucuronidase domain	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
A	d6u7ja1	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
A	d6u7ja3	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
A	d6u7ja4	Artifacts	Tags	Tags	Tags	N-terminal Tags	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
B	d6u7jb2	All beta proteins	Immunoglobulin-like beta-sandwich	beta-Galactosidase/glucuronidase domain	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
B	d6u7jb1	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
B	d6u7jb3	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
B	d6u7jb4	Artifacts	Tags	Tags	Tags	N-terminal Tags	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
C	d6u7jc2	All beta proteins	Immunoglobulin-like beta-sandwich	beta-Galactosidase/glucuronidase domain	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
C	d6u7jc1	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
C	d6u7jc3	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
C	d6u7jc4	Artifacts	Tags	Tags	Tags	N-terminal Tags	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
D	d6u7jd2	All beta proteins	Immunoglobulin-like beta-sandwich	beta-Galactosidase/glucuronidase domain	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
D	d6u7jd1	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
D	d6u7jd3	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	automated matches	automated matches	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)
D	d6u7jd4	Artifacts	Tags	Tags	Tags	N-terminal Tags	(uncultured Clostridium sp. ) [TaxId: 59620 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Glyco_hydro_2_N	e6u7jA2	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: Glyco_hydro_2_N	ECOD (1.6)
A	Glyco_hydro_2	e6u7jA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Glyco_hydro_2	ECOD (1.6)
A	Glyco_hydro_2_C	e6u7jA3	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_2_C	ECOD (1.6)
B	Glyco_hydro_2_N	e6u7jB2	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: Glyco_hydro_2_N	ECOD (1.6)
B	Glyco_hydro_2	e6u7jB3	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Glyco_hydro_2	ECOD (1.6)
B	Glyco_hydro_2_C	e6u7jB1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_2_C	ECOD (1.6)
C	Glyco_hydro_2_N	e6u7jC1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: Glyco_hydro_2_N	ECOD (1.6)
C	Glyco_hydro_2	e6u7jC2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Glyco_hydro_2	ECOD (1.6)
C	Glyco_hydro_2_C	e6u7jC3	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_2_C	ECOD (1.6)
D	Glyco_hydro_2_N	e6u7jD3	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: Glyco_hydro_2_N	ECOD (1.6)
D	Glyco_hydro_2	e6u7jD2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Glyco_hydro_2	ECOD (1.6)
D	Glyco_hydro_2_C	e6u7jD1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_2_C	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF02836	Glycosyl hydrolases family 2, TIM barrel domain (Glyco_hydro_2_C)	Glycosyl hydrolases family 2, TIM barrel domain	This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.	Domain
A, B, C, D	PF00703	Glycosyl hydrolases family 2 (Glyco_hydro_2)	Glycosyl hydrolases family 2	This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.	Domain
A, B, C, D	PF02837	Glycosyl hydrolases family 2, sugar binding domain (Glyco_hydro_2_N)	Glycosyl hydrolases family 2, sugar binding domain	This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Beta-glucuronidase	hydrolase activity, acting on glycosyl bonds beta-galactosidase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity galactosidase activity	carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR036156	Beta-Galactosidase/glucuronidase domain superfamily	Homologous Superfamily
A, B, C, D	IPR006104	Glycosyl hydrolases family 2, sugar binding domain	Domain
A, B, C, D	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A, B, C, D	IPR006103	Glycoside hydrolase family 2, catalytic domain	Domain
A, B, C, D	IPR023232	Glycoside hydrolase, family 2, active site	Active Site
A, B, C, D	IPR023230	Glycoside hydrolase, family 2, conserved site	Conserved Site
A, B, C, D	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A, B, C, D	IPR006101	Glycoside hydrolase, family 2	Family
A, B, C, D	IPR008979	Galactose-binding-like domain superfamily	Homologous Superfamily
A, B, C, D	IPR006102	Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.