Annotations: 3JCM

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
J [auth R]	d3jcmr_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	D3 core SNRNP protein	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
Q [auth J]	d3jcmj_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	D3 core SNRNP protein	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
K [auth S]	d3jcms_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	B core SNRNP protein	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
R [auth O]	d3jcmo_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	B core SNRNP protein	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
L [auth T]	d3jcmt_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	D1 core SNRNP protein	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
S [auth P]	d3jcmp_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	D1 core SNRNP protein	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
M [auth U]	d3jcmu_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	D2 core SNRNP protein	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
T [auth Q]	d3jcmq_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	D2 core SNRNP protein	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
N [auth V]	d3jcmv_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	Small nuclear ribonucleoprotein E	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
U [auth Y]	d3jcmy_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	Small nuclear ribonucleoprotein E	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
O [auth W]	d3jcmw_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	Small nuclear ribonucleoprotein F, Smf	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
V [auth Z]	d3jcmz_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	Small nuclear ribonucleoprotein F, Smf	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)
P [auth X]	d3jcmx_	All beta proteins	Sm-like fold	Sm-like ribonucleoproteins	Sm motif of small nuclear ribonucleoproteins, SNRNP	Small nuclear ribonucleoprotein G	(Saccharomyces cerevisiae S288C ) [TaxId: 559292 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	JAB1/MPN domain-like	8053281	3001105	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Ribonuclease H-like	8040983	3000143	SCOP2B (2022-06-29)
F [auth L]	SCOP2B Superfamily	Thioredoxin-like	8083616	3000031	SCOP2B (2022-06-29)
G [auth M]	SCOP2B Superfamily	L30e-like	8033484	3001739	SCOP2B (2022-06-29)
J [auth R]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8098694	3000419	SCOP2B (2022-06-29)
Q [auth J]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8098694	3000419	SCOP2B (2022-06-29)
S [auth P]	SCOP2 Family	Sm motif of small nuclear ribonucleoproteins SNRNP	8082630	4001809	SCOP2 (2022-06-29)
S [auth P]	SCOP2 Superfamily	Sm-like ribonucleoproteins	8082631	3000419	SCOP2 (2022-06-29)
M [auth U]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8063490	3000419	SCOP2B (2022-06-29)
T [auth Q]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8063490	3000419	SCOP2B (2022-06-29)
O [auth W]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8043703	3000419	SCOP2B (2022-06-29)
V [auth Z]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8043703	3000419	SCOP2B (2022-06-29)
P [auth X]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8098668	3000419	SCOP2B (2022-06-29)
W [auth a]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8098668	3000419	SCOP2B (2022-06-29)
Z [auth d]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8063446	3000419	SCOP2B (2022-06-29)
AA [auth e]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8099110	3000419	SCOP2B (2022-06-29)
BA [auth f]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8063464	3000419	SCOP2B (2022-06-29)
CA [auth g]	SCOP2B Superfamily	Sm-like ribonucleoproteins	8063498	3000419	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF10596,PF10597	e3jcmA3	A: alpha bundles	X: helical bundle domain in reverse transcriptase-like polymerases (From Topology)	H: helical bundle domain in reverse transcriptase-like polymerases (From Topology)	T: helical bundle domain in reverse transcriptase-like polymerases	F: PF10596,PF10597	ECOD (1.6)
A	PF08082,PF08083	e3jcmA1	A: alpha complex topology	X: Pre-mRNA-splicing factor 8 N-terminal domain (From Topology)	H: Pre-mRNA-splicing factor 8 N-terminal domain (From Topology)	T: Pre-mRNA-splicing factor 8 N-terminal domain	F: PF08082,PF08083	ECOD (1.6)
A	PF10598	e3jcmA2	A: a+b two layers	X: Alpha-beta plaits	H: Adenylyl and guanylyl cyclase catalytic domain-like	T: Adenylyl and guanylyl cyclase catalytic domain-like	F: PF10598	ECOD (1.6)
A	PF08084	e3jcmA5	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: PF08084	ECOD (1.6)
A	PF10596	e3jcmA6	A: a/b three-layered sandwiches	X: Restriction endonuclease-like	H: Restriction endonuclease-like (From Topology)	T: Restriction endonuclease-like	F: PF10596	ECOD (1.6)
A	PF12134	e3jcmA4	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF12134	ECOD (1.6)
B	PF00400	e3jcmB3	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: PF00400	ECOD (1.6)
C [auth I]	PF01798	e3jcmI1	A: alpha arrays	X: HhH/H2TH	H: SAM/DNA-glycosylase	T: Nop C-terminal domain	F: PF01798	ECOD (1.6)
C [auth I]	PF01798	e3jcmI3	A: alpha complex topology	X: Nop N-terminal domain (From Topology)	H: Nop N-terminal domain (From Topology)	T: Nop N-terminal domain	F: PF01798	ECOD (1.6)
C [auth I]	PF09785	e3jcmI2	A: extended segments	X: Pre-mRNA-processing factor 31 C-terminal region (From Topology)	H: Pre-mRNA-processing factor 31 C-terminal region (From Topology)	T: Pre-mRNA-processing factor 31 C-terminal region	F: PF09785	ECOD (1.6)
D [auth G]	F_UNCLASSIFIED	e3jcmG1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: F_UNCLASSIFIED	ECOD (1.6)
E [auth K]	PF06544	e3jcmK1	A: a+b two layers	X: Alpha-beta plaits	H: Acylphosphatase-like (From Topology)	T: Acylphosphatase-like	F: PF06544	ECOD (1.6)
E [auth K]	PF08572	e3jcmK2	A: extended segments	X: U4/U6 small nuclear ribonucleoprotein PRP3 N-terminal region (From Topology)	H: U4/U6 small nuclear ribonucleoprotein PRP3 N-terminal region (From Topology)	T: U4/U6 small nuclear ribonucleoprotein PRP3 N-terminal region	F: PF08572	ECOD (1.6)
F [auth L]	PF02966	e3jcmL1	A: a+b three layers	X: Thioredoxin-like	H: Thioredoxin-like (From Topology)	T: Thioredoxin-like	F: PF02966	ECOD (1.6)
G [auth M]	PF01248	e3jcmM1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: L30e-like (From Topology)	T: L30e-like	F: PF01248	ECOD (1.6)
H	F_UNCLASSIFIED	e3jcmH2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: F_UNCLASSIFIED	ECOD (1.6)
H	PF03764	e3jcmH5	A: a+b two layers	X: Ribosomal protein S5 domain 2-like (From Topology)	H: Ribosomal protein S5 domain 2-like (From Topology)	T: Ribosomal protein S5 domain 2-like	F: PF03764	ECOD (1.6)
H	F_UNCLASSIFIED	e3jcmH4	A: a+b two layers	X: Alpha-beta plaits	H: EF-G C-terminal domain-like (From Topology)	T: EF-G C-terminal domain-like	F: F_UNCLASSIFIED	ECOD (1.6)
H	PF00679	e3jcmH3	A: a+b two layers	X: Alpha-beta plaits	H: EF-G C-terminal domain-like (From Topology)	T: EF-G C-terminal domain-like	F: PF00679	ECOD (1.6)
H	PF00009	e3jcmH1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00009	ECOD (1.6)
I [auth N]	PF02889	e3jcmN7	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PF02889	ECOD (1.6)
I [auth N]	F_UNCLASSIFIED	e3jcmN5	A: alpha arrays	X: HTH	H: HTH	T: winged	F: F_UNCLASSIFIED	ECOD (1.6)
I [auth N]	F_UNCLASSIFIED	e3jcmN3	A: alpha arrays	X: HhH/H2TH	H: SAM-like subdomain in Sec63-like proteins (From Topology)	T: SAM-like subdomain in Sec63-like proteins	F: F_UNCLASSIFIED	ECOD (1.6)
I [auth N]	PF02889	e3jcmN6	A: alpha arrays	X: Sec63 N-terminal subdomain-like (From Topology)	H: Sec63 N-terminal subdomain-like (From Topology)	T: Sec63 N-terminal subdomain-like	F: PF02889	ECOD (1.6)
I [auth N]	F_UNCLASSIFIED	e3jcmN1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: F_UNCLASSIFIED	ECOD (1.6)
I [auth N]	PF00270	e3jcmN8	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00270	ECOD (1.6)
I [auth N]	PF00271	e3jcmN10	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00271	ECOD (1.6)
J [auth R]	PF01423	e3jcmR1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
Q [auth J]	PF01423	e3jcmJ1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
K [auth S]	PF01423	e3jcmS1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
R [auth O]	PF01423	e3jcmO1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
L [auth T]	PF01423	e3jcmT1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
S [auth P]	PF01423	e3jcmP1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
M [auth U]	PF01423	e3jcmU1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
T [auth Q]	PF01423	e3jcmQ1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
N [auth V]	PF01423	e3jcmV1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
U [auth Y]	PF01423	e3jcmY1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
O [auth W]	PF01423	e3jcmW1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
V [auth Z]	PF01423	e3jcmZ1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
P [auth X]	PF01423	e3jcmX1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
W [auth a]	PF01423	e3jcma1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
X [auth b]	PF01423	e3jcmb1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
Y [auth c]	PF01423	e3jcmc1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
Z [auth d]	PF01423	e3jcmd1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
AA [auth e]	PF01423	e3jcme1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
BA [auth f]	PF01423	e3jcmf1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
CA [auth g]	PF01423	e3jcmg1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)
DA [auth h]	PF01423	e3jcmh1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01423	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
F [auth L]	3.40.30.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaredoxin	Glutaredoxin	CATH (4.3.0)
G [auth M]	3.30.1330.30	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (4.3.0)
H	3.30.70.870	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Elongation Factor G (Translational Gtpase), domain 3	CATH (4.3.0)
I [auth N]	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)
I [auth N]	1.10.10.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	CATH (4.3.0)
I [auth N]	1.10.3380.10	Mainly Alpha	Orthogonal Bundle	Sec63 N-terminal domain-like fold	Sec63 N-terminal domain-like domain	CATH (4.3.0)
I [auth N]	1.10.150.20	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
I [auth N]	2.60.40.150	Mainly Beta	Sandwich	Immunoglobulin-like	C2 domain	CATH (4.3.0)
J [auth R]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
Q [auth J]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
L [auth T]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
S [auth P]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
M [auth U]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
T [auth Q]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
N [auth V]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
U [auth Y]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
O [auth W]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
V [auth Z]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
P [auth X]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
W [auth a]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
X [auth b]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
Y [auth c]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
Z [auth d]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
AA [auth e]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
BA [auth f]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
CA [auth g]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
DA [auth h]	2.30.30.100	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF10597	U5-snRNA binding site 2 of PrP8 (U5_2-snRNA_bdg)	U5-snRNA binding site 2 of PrP8	The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis [1]. This close association with crucial RNA sequences, together with extensive genetic evidence, suggests that ...	The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis [1]. This close association with crucial RNA sequences, together with extensive genetic evidence, suggests that Prp8 could directly affect the function of the catalytic core, perhaps acting as a splicing cofactor [2].	Domain
A	PF10598	RNA recognition motif of the spliceosomal PrP8 (RRM_4)	RNA recognition motif of the spliceosomal PrP8	The large RNA-protein complex of the spliceosome catalyses pre-mRNA splicing. One of the most conserved core proteins is PrP8 which occupies a central position in the catalytic core of the spliceosome, and has been implicated in several crucial molec ...	The large RNA-protein complex of the spliceosome catalyses pre-mRNA splicing. One of the most conserved core proteins is PrP8 which occupies a central position in the catalytic core of the spliceosome, and has been implicated in several crucial molecular rearrangements that occur there, and has recently come under the spotlight for its role in the inherited human disease, Retinitis Pigmentosa [1]. The RNA-recognition motif of PrP8 is highly conserved and provides a possible RNA binding centre for the 5-prime SS, BP, or 3-prime SS of pre-mRNA which are known to contact with Prp8. The most conserved regions of an RRM are defined as the RNP1 and RNP2 sequences. Recognition of RNA targets can also be modulated by a number of other factors, most notably the two loops beta1-alpha1, beta2-beta3 and the amino acid residues C-terminal to the RNP2 domain [2].	Domain
A	PF10596	U6-snRNA interacting domain of PrP8 (U6-snRNA_bdg)	U6-snRNA interacting domain of PrP8	This domain incorporates the interacting site for the U6-snRNA as part of the U4/U6.U5 tri-snRNPs complex of the spliceosome, and is the prime candidate for the role of cofactor for the spliceosome's RNA core. The essential spliceosomal protein Prp8 ...	This domain incorporates the interacting site for the U6-snRNA as part of the U4/U6.U5 tri-snRNPs complex of the spliceosome, and is the prime candidate for the role of cofactor for the spliceosome's RNA core. The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis. This close association with crucial RNA sequences, together with extensive genetic evidence, suggests that Prp8 could directly affect the function of the catalytic core, perhaps acting as a splicing cofactor [1].	Domain
A	PF12134	PRP8 domain IV core (PRP8_domainIV)	PRP8 domain IV core	This domain is found in eukaryotes, and is about 20 amino acids in length. It is found associated with Pfam:PF10597, Pfam:PF10596, Pfam:PF10598, Pfam:PF08083, Pfam:PF08082, Pfam:PF01398, Pfam:PF08084. There is a conserved LILR sequence motif. The dom ...	This domain is found in eukaryotes, and is about 20 amino acids in length. It is found associated with Pfam:PF10597, Pfam:PF10596, Pfam:PF10598, Pfam:PF08083, Pfam:PF08082, Pfam:PF01398, Pfam:PF08084. There is a conserved LILR sequence motif. The domain is a selenomethionine domain in a subunit of the spliceosome. The function of PRP8 domain IV is believed to be interaction with the splicosomal core.	Domain
A	PF08082	PRO8NT (NUC069), PrP8 N-terminal domain (PRO8NT)	PRO8NT (NUC069), PrP8 N-terminal domain	The PRO8NT domain is found at the N-terminus of pre-mRNA splicing factors of PRO8 family [1]. The NLS or nuclear localisation signal for these spliceosome proteins begins at the start and runs for 60 residues. N-terminal to this domain is a highly va ...	The PRO8NT domain is found at the N-terminus of pre-mRNA splicing factors of PRO8 family [1]. The NLS or nuclear localisation signal for these spliceosome proteins begins at the start and runs for 60 residues. N-terminal to this domain is a highly variable proline-rich region [4].	Domain
A	PF08083	PROCN (NUC071) domain (PROCN)	PROCN (NUC071) domain	The PROCN domain is the central domain in pre-mRNA splicing factors of PRO8 family [1].	Domain
A	PF08084	PROCT (NUC072) domain (PROCT)	PROCT (NUC072) domain	The PROCT domain is the C-terminal domain in pre-mRNA splicing factors of PRO8 family [1].	Domain
B	PF00400	WD domain, G-beta repeat (WD40)	WD domain, G-beta repeat	-	Repeat
C [auth I]	PF09785	Prp31 C terminal domain (Prp31_C)	Prp31 C terminal domain	-	Family
C [auth I]	PF01798	snoRNA binding domain, fibrillarin (Nop)	snoRNA binding domain, fibrillarin	-	Family
D [auth G]	PF06424	PRP1 splicing factor, N-terminal (PRP1_N)	PRP1 splicing factor, N-terminal	This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N terminus of the RNA splicing f ...	This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N terminus of the RNA splicing factor encoded by prp1 [1]. It is involved in mRNA splicing and possibly also poly(A)and RNA nuclear export and cell cycle progression.	Domain
E [auth K]	PF08572	pre-mRNA processing factor 3 domain (PRP3)	pre-mRNA processing factor 3 domain	This domain is found in U4/U6 and U4/U5/U6-small nuclear ribonucleoprotein Prp3, part of the tri-RNA complex that form the spliceosome. Prp3 plays a key role in the recognition of the snRNA duplex. The pre-mRNA processing factor 3 (PRP3) domain, resp ...	This domain is found in U4/U6 and U4/U5/U6-small nuclear ribonucleoprotein Prp3, part of the tri-RNA complex that form the spliceosome. Prp3 plays a key role in the recognition of the snRNA duplex. The pre-mRNA processing factor 3 (PRP3) domain, responsible for the binding to stem II of the snRNA duplex, is highly conserved among eukaryotes and is found N-terminal to Pfam:PF06544 [3,4]. The human PRP3 has been implicated in autosomal retinitis pigmentosa [2].	Domain
E [auth K]	PF06544	Small nuclear ribonucleoprotein Prp3, C-terminal domain (Prp3_C)	Small nuclear ribonucleoprotein Prp3, C-terminal domain	This domain is found at the C-terminal end of U4/U6 and U4/U5/U6- small nuclear ribonucleoprotein Prp3, part of the tri-RNA complex that form the spliceosome. Prp3 plays a key role in the recognition of the snRNA duplex. This binding domain, highly c ...	This domain is found at the C-terminal end of U4/U6 and U4/U5/U6- small nuclear ribonucleoprotein Prp3, part of the tri-RNA complex that form the spliceosome. Prp3 plays a key role in the recognition of the snRNA duplex. This binding domain, highly conserved among eukaryotes, interacts with the 3' end of U6 snRNA. It adopts a ferredoxin-like fold, showing a five-stranded mixed beta-sheet with three alpha-helices, two of them running parallel to the beta-strands on one side of the sheet and one on the other. This fold is extended with a long beta-hairpin, an extra beta-strand, an helix and a final loop at the C terminus. It is located C-terminal to Pfam:PF08572 [1-4].	Domain
F [auth L]	PF02966	Mitosis protein DIM1 (DIM1)	Mitosis protein DIM1	-	Domain
G [auth M]	PF01248	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...	This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].	Domain
H	PF00679	Elongation factor G C-terminus (EFG_C)	Elongation factor G C-terminus	This domain includes the carboxyl terminal regions of Elongation factor G, elongation factor 2 and some tetracycline resistance proteins and adopt a ferredoxin-like fold.	Domain
H	PF00009	Elongation factor Tu GTP binding domain (GTP_EFTU)	Elongation factor Tu GTP binding domain	This domain contains a P-loop motif, also found in several other families such as Pfam:PF00071, Pfam:PF00025 and Pfam:PF00063. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains.	Domain
H	PF16004	116 kDa U5 small nuclear ribonucleoprotein component N-terminus (EFTUD2)	116 kDa U5 small nuclear ribonucleoprotein component N-terminus	-	Family
H	PF03764	Elongation factor G, domain IV (EFG_IV)	Elongation factor G, domain IV	This domain is found in elongation factor G, elongation factor 2 and some tetracycline resistance proteins and adopts a ribosomal protein S5 domain 2-like fold.	Domain
I [auth N]	PF02889	Sec63 Brl domain (Sec63)	Sec63 Brl domain	-	Family
I [auth N]	PF00270	DEAD/DEAH box helicase (DEAD)	DEAD/DEAH box helicase	Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome ...	Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.	Domain
I [auth N]	PF00271	Helicase conserved C-terminal domain (Helicase_C)	Helicase conserved C-terminal domain	The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.	Domain
J [auth R], Q [auth J]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
K [auth S], R [auth O]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
L [auth T], S [auth P]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
M [auth U], T [auth Q]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
N [auth V], U [auth Y]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
O [auth W], V [auth Z]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
P [auth X], W [auth a]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
X [auth b]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
Y [auth c]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
Z [auth d]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
AA [auth e]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
BA [auth f]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
CA [auth g]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain
DA [auth h]	PF01423	LSM domain (LSM)	LSM domain	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) i ...	The LSM domain contains Sm proteins as well as other related LSM (Like Sm) proteins. The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B', D1, D2, D3, E, F and G) in common, which assemble around the Sm site present in four of the major spliceosomal small nuclear RNAs. The U6 snRNP binds to the LSM (Like Sm) proteins [3]. Sm proteins are also found in archaebacteria, which do not have any splicing apparatus suggesting a more general role for Sm proteins. All Sm proteins contain a common sequence motif in two segments, Sm1 and Sm2, separated by a short variable linker. This family also includes the bacterial Hfq (host factor Q) proteins. Hfq are also RNA-binding proteins, that form hexameric rings.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Pre-mRNA-splicing factor 8	peptidase activity catalytic activity, acting on a protein metallopeptidase activity hydrolase activity catalytic activity RNA binding snRNA binding binding organic cyclic compound binding nucleic acid binding U1 snRNA binding U6 snRNA binding mRNA binding U5 snRNA binding peptidase activity catalytic activity, acting on a protein metallopeptidase activity hydrolase activity catalytic activity RNA binding snRNA binding binding organic cyclic compound binding nucleic acid binding U1 snRNA binding U6 snRNA binding mRNA binding U5 snRNA binding U2 snRNA binding pre-mRNA binding pre-mRNA intronic binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing spliceosomal tri-snRNP complex assembly protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing spliceosomal tri-snRNP complex assembly protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization spliceosomal snRNP assembly cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal complex assembly mRNA splice site recognition mRNA 3'-splice site recognition mRNA 5'-splice site recognition mRNA cis splicing, via spliceosome generation of catalytic spliceosome for second transesterification step spliceosomal conformational changes to generate catalytic conformation	membrane-bounded organelle catalytic step 2 spliceosome protein-containing complex intracellular anatomical structure catalytic complex nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle spliceosomal complex organelle ribonucleoprotein complex cytoplasm membrane-bounded organelle catalytic step 2 spliceosome protein-containing complex intracellular anatomical structure catalytic complex nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle spliceosomal complex organelle ribonucleoprotein complex cytoplasm spliceosomal snRNP complex Sm-like protein family complex U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex small nuclear ribonucleoprotein complex U5 snRNP
B	U4/U6 small nuclear ribonucleoprotein PRP4	RNA binding U6 snRNA binding snRNA binding binding organic cyclic compound binding nucleic acid binding U4 snRNA binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal conformational changes to generate catalytic conformation sno(s)RNA processing sno(s)RNA metabolic process nucleic acid catabolic process snoRNA splicing	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex spliceosomal complex U4/U6 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex
C [auth I]	Pre-mRNA-processing factor 31	RNA binding binding organic cyclic compound binding nucleic acid binding	RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome organic substance biosynthetic process metabolic process cellular process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process RNA processing ribonucleoprotein complex biogenesis spliceosomal tri-snRNP complex assembly protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular component organization or biogenesis protein-containing complex organization spliceosomal snRNP assembly	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle spliceosomal snRNP complex protein-containing complex nucleus nuclear protein-containing complex Sm-like protein family complex U4 snRNP membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle spliceosomal snRNP complex protein-containing complex nucleus nuclear protein-containing complex Sm-like protein family complex U4 snRNP small nuclear ribonucleoprotein complex ribonucleoprotein complex spliceosomal complex precatalytic spliceosome U4/U6 snRNP spliceosomal tri-snRNP complex U4/U6 x U5 tri-snRNP complex
D [auth G]	Pre-mRNA-splicing factor 6	-	RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome organic substance biosynthetic process metabolic process cellular process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process RNA processing ribonucleoprotein complex biogenesis spliceosomal tri-snRNP complex assembly protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular component organization or biogenesis protein-containing complex organization spliceosomal snRNP assembly	membrane-bounded organelle catalytic step 2 spliceosome protein-containing complex intracellular anatomical structure catalytic complex nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle spliceosomal complex organelle ribonucleoprotein complex spliceosomal snRNP complex membrane-bounded organelle catalytic step 2 spliceosome protein-containing complex intracellular anatomical structure catalytic complex nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle spliceosomal complex organelle ribonucleoprotein complex spliceosomal snRNP complex Sm-like protein family complex small nuclear ribonucleoprotein complex U4/U6 snRNP U5 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex
E [auth K]	U4/U6 small nuclear ribonucleoprotein PRP3	-	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal snRNP assembly	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex U4/U6 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex spliceosomal complex
F [auth L]	Spliceosomal protein DIB1	-	RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome organic substance biosynthetic process metabolic process cellular process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process RNA processing	U5 snRNP membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex U5 snRNP membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex spliceosomal complex
G [auth M]	13 kDa ribonucleoprotein-associated protein	RNA binding binding U3 snoRNA binding organic cyclic compound binding snoRNA binding nucleic acid binding snRNA binding U4 snRNA binding	ribonucleoprotein complex biogenesis snoRNA guided rRNA 2'-O-methylation cellular biosynthetic process rRNA methylation RNA metabolic process rRNA processing rRNA modification nucleobase-containing compound metabolic process cellular component biogenesis ribosome biogenesis organic substance metabolic process organic substance biosynthetic process cellular component organization or biogenesis RNA processing ribonucleoprotein complex biogenesis snoRNA guided rRNA 2'-O-methylation cellular biosynthetic process rRNA methylation RNA metabolic process rRNA processing rRNA modification nucleobase-containing compound metabolic process cellular component biogenesis ribosome biogenesis organic substance metabolic process organic substance biosynthetic process cellular component organization or biogenesis RNA processing rRNA metabolic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process nucleic acid metabolic process macromolecule methylation organic cyclic compound metabolic process RNA modification biosynthetic process methylation macromolecule modification nucleic acid catabolic process metabolic process cellular process macromolecule metabolic process rRNA 2'-O-methylation RNA methylation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of SSU-rRNA ribosomal small subunit biogenesis sno(s)RNA metabolic process box C/D sno(s)RNA 3'-end processing RNA 3'-end processing sno(s)RNA processing box C/D sno(s)RNA metabolic process box C/D sno(s)RNA processing sno(s)RNA 3'-end processing ribosomal large subunit biogenesis maturation of LSU-rRNA positive regulation of molecular function regulation of molecular function positive regulation of RNA binding regulation of binding biological regulation positive regulation of binding regulation of RNA binding mRNA processing protein-RNA complex assembly cellular component organization spliceosomal complex assembly protein-RNA complex organization cellular component assembly protein-containing complex assembly RNA splicing protein-containing complex organization mRNA metabolic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-enclosed lumen nucleolus intracellular organelle lumen organelle lumen intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle spliceosomal complex precatalytic spliceosome U4/U6 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex nucleoplasm box C/D methylation guide snoRNP complex sno(s)RNA-containing ribonucleoprotein complex box C/D RNP complex preribosome small-subunit processome ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome ribosome cytoplasm cytosol large ribosomal subunit
H	Pre-mRNA-splicing factor SNU114	binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding organic cyclic compound binding purine nucleotide binding anion binding heterocyclic compound binding carbohydrate derivative binding binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding organic cyclic compound binding purine nucleotide binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding RNA binding snRNA binding U5 snRNA binding nucleic acid binding pyrophosphatase activity GTPase activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing generation of catalytic spliceosome for first transesterification step protein-containing complex organization cellular metabolic process spliceosomal conformational changes to generate catalytic conformation primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal tri-snRNP complex assembly spliceosomal snRNP assembly spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol membrane-bounded organelle spliceosomal snRNP complex protein-containing complex nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle intracellular organelle U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex intracellular anatomical structure cytoplasm cellular anatomical entity cytosol membrane-bounded organelle spliceosomal snRNP complex protein-containing complex nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle intracellular organelle U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex spliceosomal complex U5 snRNP U2-type spliceosomal complex catalytic step 2 spliceosome catalytic complex U2-type catalytic step 2 spliceosome
I [auth N]	Pre-mRNA-splicing helicase BRR2	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding nucleic acid binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid helicase activity RNA helicase activity ATP-dependent activity, acting on RNA identical protein binding protein binding	RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome organic substance biosynthetic process metabolic process cellular process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process RNA processing ribonucleoprotein complex biogenesis protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular component organization or biogenesis spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) protein-containing complex organization spliceosomal conformational changes to generate catalytic conformation	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle spliceosomal complex organelle ribonucleoprotein complex U5 snRNP spliceosomal snRNP complex Sm-like protein family complex membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle spliceosomal complex organelle ribonucleoprotein complex U5 snRNP spliceosomal snRNP complex Sm-like protein family complex small nuclear ribonucleoprotein complex U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex
J [auth R], Q [auth J]	Small nuclear ribonucleoprotein Sm D3	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions U2-type prespliceosome assembly mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal snRNP assembly mRNA splice site recognition mRNA 5'-splice site recognition mRNA cis splicing, via spliceosome RNA capping 7-methylguanosine cap hypermethylation macromolecule methylation RNA modification methylation macromolecule modification RNA 5'-end processing RNA methylation	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex pICln-Sm protein complex cytoplasm spliceosomal complex precatalytic spliceosome U2 snRNP catalytic step 2 spliceosome catalytic complex cytosol U4/U6 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex U1 snRNP SMN-Sm protein complex U5 snRNP U2-type spliceosomal complex commitment complex prespliceosome U2-type prespliceosome
K [auth S], R [auth O]	Small nuclear ribonucleoprotein-associated protein B	RNA binding binding organic cyclic compound binding nucleic acid binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process mRNA splice site recognition mRNA 5'-splice site recognition mRNA cis splicing, via spliceosome RNA capping 7-methylguanosine cap hypermethylation macromolecule methylation RNA modification methylation macromolecule modification RNA 5'-end processing RNA methylation U2-type prespliceosome assembly spliceosomal snRNP assembly	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex U2 snRNP catalytic step 2 spliceosome catalytic complex spliceosomal complex U4/U6 snRNP U5 snRNP U2-type spliceosomal complex commitment complex cytoplasm U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex prespliceosome U2-type prespliceosome U1 snRNP
L [auth T], S [auth P]	Small nuclear ribonucleoprotein Sm D1	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions U2-type prespliceosome assembly mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal snRNP assembly mRNA splice site recognition mRNA 5'-splice site recognition mRNA cis splicing, via spliceosome RNA capping 7-methylguanosine cap hypermethylation macromolecule methylation RNA modification methylation macromolecule modification RNA 5'-end processing RNA methylation	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex pICln-Sm protein complex cytoplasm spliceosomal complex precatalytic spliceosome U2 snRNP catalytic step 2 spliceosome catalytic complex cytosol U4/U6 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex U1 snRNP SMN-Sm protein complex U5 snRNP U2-type spliceosomal complex commitment complex prespliceosome U2-type prespliceosome
M [auth U], T [auth Q]	Small nuclear ribonucleoprotein Sm D2	RNA binding binding organic cyclic compound binding nucleic acid binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions U2-type prespliceosome assembly mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal snRNP assembly mRNA splice site recognition mRNA 5'-splice site recognition mRNA cis splicing, via spliceosome RNA capping 7-methylguanosine cap hypermethylation macromolecule methylation RNA modification methylation macromolecule modification RNA 5'-end processing RNA methylation	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex pICln-Sm protein complex cytoplasm spliceosomal complex precatalytic spliceosome U2 snRNP catalytic step 2 spliceosome catalytic complex cytosol U4/U6 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex U1 snRNP U5 snRNP U2-type spliceosomal complex commitment complex prespliceosome U2-type prespliceosome
N [auth V], U [auth Y]	Small nuclear ribonucleoprotein E	RNA binding binding organic cyclic compound binding nucleic acid binding splicing factor binding protein binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions U2-type prespliceosome assembly mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal snRNP assembly mRNA splice site recognition mRNA 5'-splice site recognition mRNA cis splicing, via spliceosome RNA capping 7-methylguanosine cap hypermethylation macromolecule methylation RNA modification methylation macromolecule modification RNA 5'-end processing RNA methylation	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex pICln-Sm protein complex cytoplasm spliceosomal complex precatalytic spliceosome U2 snRNP U4/U6 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex U1 snRNP U5 snRNP U2-type spliceosomal complex commitment complex prespliceosome U2-type prespliceosome
O [auth W], V [auth Z]	Small nuclear ribonucleoprotein F	RNA binding binding organic cyclic compound binding nucleic acid binding splicing factor binding protein binding poly-pyrimidine tract binding poly(U) RNA binding single-stranded RNA binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions U2-type prespliceosome assembly mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal snRNP assembly mRNA splice site recognition mRNA 5'-splice site recognition mRNA cis splicing, via spliceosome RNA capping 7-methylguanosine cap hypermethylation macromolecule methylation RNA modification methylation macromolecule modification RNA 5'-end processing RNA methylation	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex pICln-Sm protein complex cytoplasm U2 snRNP catalytic step 2 spliceosome catalytic complex spliceosomal complex U4/U6 snRNP U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex U1 snRNP U5 snRNP U2-type spliceosomal complex commitment complex
P [auth X], W [auth a]	Small nuclear ribonucleoprotein G	RNA binding binding organic cyclic compound binding nucleic acid binding	ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process ribonucleoprotein complex biogenesis cellular biosynthetic process RNA metabolic process mRNA processing protein-RNA complex assembly cellular component organization cellular component biogenesis nucleobase-containing compound metabolic process spliceosomal complex assembly protein-RNA complex organization cellular component assembly organic substance metabolic process protein-containing complex assembly organic substance biosynthetic process cellular component organization or biogenesis RNA processing RNA splicing protein-containing complex organization cellular metabolic process primary metabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound metabolic process biosynthetic process RNA splicing, via transesterification reactions U2-type prespliceosome assembly mRNA splicing, via spliceosome cellular process metabolic process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process spliceosomal snRNP assembly mRNA splice site recognition mRNA 5'-splice site recognition mRNA cis splicing, via spliceosome RNA capping 7-methylguanosine cap hypermethylation macromolecule methylation RNA modification methylation macromolecule modification RNA 5'-end processing RNA methylation	membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex membrane-bounded organelle spliceosomal snRNP complex protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex Sm-like protein family complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle U4 snRNP small nuclear ribonucleoprotein complex organelle ribonucleoprotein complex spliceosomal complex precatalytic spliceosome U2 snRNP catalytic step 2 spliceosome catalytic complex U4/U6 snRNP cytoplasm U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex U1 snRNP SMN-Sm protein complex U5 snRNP U2-type spliceosomal complex commitment complex prespliceosome U2-type prespliceosome
X [auth b]	U6 snRNA-associated Sm-like protein LSm8	RNA binding binding organic cyclic compound binding nucleic acid binding	RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome organic substance biosynthetic process metabolic process cellular process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process RNA processing ribonucleoprotein complex biogenesis rRNA processing cellular component biogenesis ribosome biogenesis cellular component organization or biogenesis rRNA metabolic process nucleic acid catabolic process tRNA metabolic process tRNA processing	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle protein-containing complex nuclear protein-containing complex spliceosomal complex ribonucleoprotein complex precatalytic spliceosome spliceosomal snRNP complex U6 snRNP Sm-like protein family complex small nuclear ribonucleoprotein complex U4/U6 snRNP cytoplasm U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex
Y [auth c]	U6 snRNA-associated Sm-like protein LSm2	RNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA catabolic process regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA catabolic process regulation of biological process positive regulation of nucleobase-containing compound metabolic process cellular metabolic process negative regulation of metabolic process positive regulation of mRNA metabolic process primary metabolic process regulation of cellular metabolic process negative regulation of cellular biosynthetic process nucleobase-containing compound catabolic process positive regulation of RNA metabolic process organic cyclic compound metabolic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of macromolecule biosynthetic process nucleic acid catabolic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process deadenylation-dependent decapping of nuclear-transcribed mRNA regulation of metabolic process RNA decapping nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay catabolic process cellular biosynthetic process positive regulation of biological process RNA metabolic process macromolecule catabolic process mRNA destabilization organic substance metabolic process regulation of mRNA catabolic process negative regulation of cellular process mRNA methylguanosine-cap decapping negative regulation of macromolecule metabolic process regulation of biosynthetic process nuclear-transcribed mRNA catabolic process RNA destabilization biological regulation regulation of macromolecule metabolic process regulation of catabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound catabolic process regulation of cellular biosynthetic process positive regulation of catabolic process regulation of mRNA stability negative regulation of biosynthetic process positive regulation of mRNA catabolic process regulation of RNA stability cellular process regulation of mRNA metabolic process organic substance catabolic process RNA splicing mRNA processing RNA splicing, via transesterification reactions mRNA splicing, via spliceosome RNA splicing, via transesterification reactions with bulged adenosine as nucleophile RNA processing ribonucleoprotein complex biogenesis rRNA processing cellular component biogenesis ribosome biogenesis cellular component organization or biogenesis rRNA metabolic process tRNA metabolic process tRNA processing	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle protein-containing complex nuclear protein-containing complex spliceosomal complex ribonucleoprotein complex precatalytic spliceosome spliceosomal snRNP complex U6 snRNP Sm-like protein family complex small nuclear ribonucleoprotein complex catalytic step 2 spliceosome catalytic complex sno(s)RNA-containing ribonucleoprotein complex U4/U6 snRNP cytoplasmic ribonucleoprotein granule ribonucleoprotein granule cytoplasm supramolecular complex P-body Lsm1-7-Pat1 complex U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex
Z [auth d]	U6 snRNA-associated Sm-like protein LSm3	RNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA catabolic process regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA catabolic process regulation of biological process positive regulation of nucleobase-containing compound metabolic process cellular metabolic process negative regulation of metabolic process positive regulation of mRNA metabolic process primary metabolic process regulation of cellular metabolic process negative regulation of cellular biosynthetic process nucleobase-containing compound catabolic process positive regulation of RNA metabolic process organic cyclic compound metabolic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of macromolecule biosynthetic process nucleic acid catabolic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process deadenylation-dependent decapping of nuclear-transcribed mRNA regulation of metabolic process RNA decapping nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay catabolic process cellular biosynthetic process positive regulation of biological process RNA metabolic process macromolecule catabolic process mRNA destabilization organic substance metabolic process regulation of mRNA catabolic process negative regulation of cellular process mRNA methylguanosine-cap decapping negative regulation of macromolecule metabolic process regulation of biosynthetic process nuclear-transcribed mRNA catabolic process RNA destabilization biological regulation regulation of macromolecule metabolic process regulation of catabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound catabolic process regulation of cellular biosynthetic process positive regulation of catabolic process regulation of mRNA stability negative regulation of biosynthetic process positive regulation of mRNA catabolic process regulation of RNA stability cellular process regulation of mRNA metabolic process organic substance catabolic process RNA splicing mRNA processing RNA splicing, via transesterification reactions mRNA splicing, via spliceosome RNA splicing, via transesterification reactions with bulged adenosine as nucleophile RNA processing ribonucleoprotein complex biogenesis rRNA processing cellular component biogenesis ribosome biogenesis cellular component organization or biogenesis rRNA metabolic process tRNA metabolic process tRNA processing cellular component organization organelle organization cellular component assembly organelle assembly P-body assembly non-membrane-bounded organelle assembly	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle protein-containing complex nuclear protein-containing complex spliceosomal complex ribonucleoprotein complex precatalytic spliceosome spliceosomal snRNP complex U6 snRNP Sm-like protein family complex small nuclear ribonucleoprotein complex catalytic step 2 spliceosome catalytic complex sno(s)RNA-containing ribonucleoprotein complex U4/U6 snRNP cytoplasmic ribonucleoprotein granule ribonucleoprotein granule cytoplasm supramolecular complex P-body Lsm1-7-Pat1 complex U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex
AA [auth e]	U6 snRNA-associated Sm-like protein LSm6	RNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA catabolic process regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA catabolic process regulation of biological process positive regulation of nucleobase-containing compound metabolic process cellular metabolic process negative regulation of metabolic process positive regulation of mRNA metabolic process primary metabolic process regulation of cellular metabolic process negative regulation of cellular biosynthetic process nucleobase-containing compound catabolic process positive regulation of RNA metabolic process organic cyclic compound metabolic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of macromolecule biosynthetic process nucleic acid catabolic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process deadenylation-dependent decapping of nuclear-transcribed mRNA regulation of metabolic process RNA decapping nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay catabolic process cellular biosynthetic process positive regulation of biological process RNA metabolic process macromolecule catabolic process mRNA destabilization organic substance metabolic process regulation of mRNA catabolic process negative regulation of cellular process mRNA methylguanosine-cap decapping negative regulation of macromolecule metabolic process regulation of biosynthetic process nuclear-transcribed mRNA catabolic process RNA destabilization biological regulation regulation of macromolecule metabolic process regulation of catabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound catabolic process regulation of cellular biosynthetic process positive regulation of catabolic process regulation of mRNA stability negative regulation of biosynthetic process positive regulation of mRNA catabolic process regulation of RNA stability cellular process regulation of mRNA metabolic process organic substance catabolic process RNA splicing mRNA processing RNA splicing, via transesterification reactions mRNA splicing, via spliceosome RNA splicing, via transesterification reactions with bulged adenosine as nucleophile RNA processing ribonucleoprotein complex biogenesis rRNA processing cellular component biogenesis ribosome biogenesis cellular component organization or biogenesis rRNA metabolic process tRNA metabolic process tRNA processing maturation of SSU-rRNA ribosomal small subunit biogenesis	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle spliceosomal snRNP complex protein-containing complex U6 snRNP nuclear protein-containing complex Sm-like protein family complex small nuclear ribonucleoprotein complex ribonucleoprotein complex spliceosomal complex sno(s)RNA-containing ribonucleoprotein complex U4/U6 snRNP cytoplasmic ribonucleoprotein granule ribonucleoprotein granule cytoplasm supramolecular complex P-body Lsm1-7-Pat1 complex U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex
BA [auth f]	U6 snRNA-associated Sm-like protein LSm5	RNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process catabolic process cellular biosynthetic process negative regulation of biological process RNA metabolic process negative regulation of cellular metabolic process macromolecule catabolic process nucleobase-containing compound metabolic process organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process RNA catabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of cellular process catabolic process cellular biosynthetic process negative regulation of biological process RNA metabolic process negative regulation of cellular metabolic process macromolecule catabolic process nucleobase-containing compound metabolic process organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process RNA catabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process mRNA catabolic process nuclear-transcribed mRNA catabolic process regulation of biological process cellular metabolic process negative regulation of metabolic process biological regulation regulation of cellular metabolic process primary metabolic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process mRNA metabolic process negative regulation of cellular biosynthetic process nucleic acid metabolic process organic cyclic compound catabolic process nucleobase-containing compound catabolic process regulation of cellular biosynthetic process regulation of gene expression organic cyclic compound metabolic process negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process nucleic acid catabolic process regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process organic substance catabolic process regulation of primary metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality positive regulation of nucleobase-containing compound metabolic process positive regulation of mRNA metabolic process positive regulation of RNA metabolic process deadenylation-dependent decapping of nuclear-transcribed mRNA RNA decapping nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay positive regulation of biological process mRNA destabilization regulation of mRNA catabolic process mRNA methylguanosine-cap decapping RNA destabilization regulation of catabolic process positive regulation of catabolic process regulation of mRNA stability positive regulation of mRNA catabolic process regulation of RNA stability regulation of mRNA metabolic process RNA splicing mRNA processing RNA splicing, via transesterification reactions mRNA splicing, via spliceosome RNA splicing, via transesterification reactions with bulged adenosine as nucleophile RNA processing ribonucleoprotein complex biogenesis rRNA processing cellular component biogenesis ribosome biogenesis cellular component organization or biogenesis rRNA metabolic process tRNA metabolic process tRNA processing	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle spliceosomal snRNP complex protein-containing complex U6 snRNP nuclear protein-containing complex Sm-like protein family complex small nuclear ribonucleoprotein complex ribonucleoprotein complex spliceosomal complex sno(s)RNA-containing ribonucleoprotein complex U4/U6 snRNP cytoplasmic ribonucleoprotein granule ribonucleoprotein granule cytoplasm supramolecular complex P-body Lsm1-7-Pat1 complex U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex
CA [auth g]	U6 snRNA-associated Sm-like protein LSm7	RNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process catabolic process cellular biosynthetic process negative regulation of biological process RNA metabolic process negative regulation of cellular metabolic process macromolecule catabolic process nucleobase-containing compound metabolic process organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process RNA catabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of cellular process catabolic process cellular biosynthetic process negative regulation of biological process RNA metabolic process negative regulation of cellular metabolic process macromolecule catabolic process nucleobase-containing compound metabolic process organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process RNA catabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process mRNA catabolic process nuclear-transcribed mRNA catabolic process regulation of biological process cellular metabolic process negative regulation of metabolic process biological regulation regulation of cellular metabolic process primary metabolic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process mRNA metabolic process negative regulation of cellular biosynthetic process nucleic acid metabolic process organic cyclic compound catabolic process nucleobase-containing compound catabolic process regulation of cellular biosynthetic process regulation of gene expression organic cyclic compound metabolic process negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process nucleic acid catabolic process regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process organic substance catabolic process regulation of primary metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality positive regulation of nucleobase-containing compound metabolic process positive regulation of mRNA metabolic process positive regulation of RNA metabolic process deadenylation-dependent decapping of nuclear-transcribed mRNA RNA decapping nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay positive regulation of biological process mRNA destabilization regulation of mRNA catabolic process mRNA methylguanosine-cap decapping RNA destabilization regulation of catabolic process positive regulation of catabolic process regulation of mRNA stability positive regulation of mRNA catabolic process regulation of RNA stability regulation of mRNA metabolic process ribonucleoprotein complex biogenesis rRNA processing cellular component biogenesis ribosome biogenesis cellular component organization or biogenesis RNA processing rRNA metabolic process tRNA metabolic process tRNA processing maturation of SSU-rRNA ribosomal small subunit biogenesis RNA splicing mRNA processing RNA splicing, via transesterification reactions mRNA splicing, via spliceosome RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle spliceosomal snRNP complex protein-containing complex U6 snRNP nuclear protein-containing complex Sm-like protein family complex small nuclear ribonucleoprotein complex ribonucleoprotein complex catalytic step 2 spliceosome catalytic complex spliceosomal complex U4/U6 snRNP cytoplasm Lsm1-7-Pat1 complex U4/U6 x U5 tri-snRNP complex spliceosomal tri-snRNP complex sno(s)RNA-containing ribonucleoprotein complex cytoplasmic ribonucleoprotein granule ribonucleoprotein granule supramolecular complex P-body U2-type spliceosomal complex prespliceosome U2-type prespliceosome
DA [auth h]	U6 snRNA-associated Sm-like protein LSm4	RNA binding U6 snRNA binding snRNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA catabolic process regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process post-transcriptional regulation of gene expression regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA catabolic process regulation of biological process positive regulation of nucleobase-containing compound metabolic process cellular metabolic process negative regulation of metabolic process positive regulation of mRNA metabolic process primary metabolic process regulation of cellular metabolic process negative regulation of cellular biosynthetic process nucleobase-containing compound catabolic process positive regulation of RNA metabolic process organic cyclic compound metabolic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of macromolecule biosynthetic process nucleic acid catabolic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process deadenylation-dependent decapping of nuclear-transcribed mRNA regulation of metabolic process RNA decapping nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay catabolic process cellular biosynthetic process positive regulation of biological process RNA metabolic process macromolecule catabolic process mRNA destabilization organic substance metabolic process regulation of mRNA catabolic process negative regulation of cellular process mRNA methylguanosine-cap decapping negative regulation of macromolecule metabolic process regulation of biosynthetic process nuclear-transcribed mRNA catabolic process RNA destabilization biological regulation regulation of macromolecule metabolic process regulation of catabolic process gene expression mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process organic cyclic compound catabolic process regulation of cellular biosynthetic process positive regulation of catabolic process regulation of mRNA stability negative regulation of biosynthetic process positive regulation of mRNA catabolic process regulation of RNA stability cellular process regulation of mRNA metabolic process organic substance catabolic process RNA splicing mRNA processing RNA splicing, via transesterification reactions mRNA splicing, via spliceosome RNA splicing, via transesterification reactions with bulged adenosine as nucleophile RNA processing ribonucleoprotein complex biogenesis rRNA processing cellular component biogenesis ribosome biogenesis cellular component organization or biogenesis rRNA metabolic process tRNA metabolic process tRNA processing cellular component organization organelle organization cellular component assembly organelle assembly P-body assembly non-membrane-bounded organelle assembly protein-RNA complex assembly protein-RNA complex organization protein-containing complex assembly protein-containing complex organization spliceosomal snRNP assembly	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle spliceosomal snRNP complex protein-containing complex U6 snRNP nuclear protein-containing complex Sm-like protein family complex small nuclear ribonucleoprotein complex ribonucleoprotein complex spliceosomal complex sno(s)RNA-containing ribonucleoprotein complex U4/U6 snRNP spliceosomal tri-snRNP complex cytoplasmic ribonucleoprotein granule ribonucleoprotein granule cytoplasm supramolecular complex P-body Lsm1-7-Pat1 complex U4/U6 x U5 tri-snRNP complex
EA [auth C]	pre-mRNA	-	-	-
FA [auth D]	SNR6 snRNA	-	-	-
GA [auth E]	SNR14 snRNA	-	-	-
HA [auth F]	SNR7-L snRNA	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR012984	PROCT domain	Domain
A	IPR012591	PRO8NT domain	Domain
A	IPR019580	Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding	Domain
A	IPR027652	Pre-mRNA-processing-splicing factor 8	Family
A	IPR043172	Prp8 RNase domain IV, palm region	Homologous Superfamily
A	IPR012592	PROCN domain	Domain
A	IPR012337	Ribonuclease H-like superfamily	Homologous Superfamily
A	IPR043173	Prp8 RNase domain IV, fingers region	Homologous Superfamily
A	IPR021983	PRP8 domain IV core	Domain
A	IPR019581	Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding	Domain
A	IPR037518	MPN domain	Domain
A	IPR019582	RNA recognition motif, spliceosomal PrP8	Domain
A	IPR042516	Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily	Homologous Superfamily
A	IPR000555	JAB1/MPN/MOV34 metalloenzyme domain	Domain
B	IPR019775	WD40 repeat, conserved site	Conserved Site
B	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
B	IPR014906	Pre-mRNA processing factor 4 (PRP4)-like	Domain
B	IPR001680	WD40 repeat	Repeat
B	IPR020472	G-protein beta WD-40 repeat	Repeat
B	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
C [auth I]	IPR042239	Nop, C-terminal domain	Homologous Superfamily
C [auth I]	IPR019175	Prp31 C-terminal	Domain
C [auth I]	IPR002687	Nop domain	Domain
C [auth I]	IPR012976	NOSIC	Domain
C [auth I]	IPR027105	U4/U6 small nuclear ribonucleoprotein Prp31	Family
C [auth I]	IPR036070	Nop domain superfamily	Homologous Superfamily
D [auth G]	IPR011990	Tetratricopeptide-like helical domain superfamily	Homologous Superfamily
D [auth G]	IPR010491	PRP1 splicing factor, N-terminal	Domain
D [auth G]	IPR003107	HAT (Half-A-TPR) repeat	Repeat
D [auth G]	IPR045075	Pre-mRNA-splicing factor Syf1-like	Family
D [auth G]	IPR019734	Tetratricopeptide repeat	Repeat
E [auth K]	IPR013881	Pre-mRNA-splicing factor 3 domain	Domain
E [auth K]	IPR027104	U4/U6 small nuclear ribonucleoprotein Prp3	Family
E [auth K]	IPR010541	Small nuclear ribonucleoprotein Prp3, C-terminal domain	Domain
F [auth L]	IPR004123	Dim1 family	Family
F [auth L]	IPR036249	Thioredoxin-like superfamily	Homologous Superfamily
G [auth M]	IPR002415	H/ACA ribonucleoprotein complex, subunit Nhp2-like	Family
G [auth M]	IPR029064	Ribosomal protein eL30-like superfamily	Homologous Superfamily
G [auth M]	IPR018492	Ribosomal protein eL8/Nhp2 family	Family
G [auth M]	IPR004038	Ribosomal protein eL8/eL30/eS12/Gadd45	Domain
G [auth M]	IPR004037	Large ribosomal subunit protein eL8-like, conserved site	Conserved Site
H	IPR005517	Translation elongation factor EFG/EF2, domain IV	Domain
H	IPR000795	Translational (tr)-type GTP-binding domain	Domain
H	IPR035647	EF-G domain III/V-like	Homologous Superfamily
H	IPR035655	116kDa U5 small nuclear ribonucleoprotein component, C-terminal	Domain
H	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
H	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	Homologous Superfamily
H	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
H	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Homologous Superfamily
H	IPR031950	116kDa U5 small nuclear ribonucleoprotein component, N-terminal	Domain
H	IPR000640	Elongation factor EFG, domain V-like	Domain
H	IPR044121	Snu114, GTP-binding domain	Domain
I [auth N]	IPR001650	Helicase, C-terminal domain-like	Domain
I [auth N]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
I [auth N]	IPR014001	Helicase superfamily 1/2, ATP-binding domain	Domain
I [auth N]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
I [auth N]	IPR048863	Pre-mRNA-splicing helicase BRR2-like, plug domain	Domain
I [auth N]	IPR041094	Brr2, N-terminal helicase PWI domain	Domain
I [auth N]	IPR004179	Sec63 domain	Domain
I [auth N]	IPR035892	C2 domain superfamily	Homologous Superfamily
I [auth N]	IPR014756	Immunoglobulin E-set	Homologous Superfamily
I [auth N]	IPR011545	DEAD/DEAH box helicase domain	Domain
I [auth N]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
J [auth R], Q [auth J]	IPR027141	Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3	Family
J [auth R], Q [auth J]	IPR034099	Small nuclear ribonucleoprotein Sm D3	Family
J [auth R], Q [auth J]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
J [auth R], Q [auth J]	IPR047575	Sm domain	Domain
J [auth R], Q [auth J]	IPR010920	LSM domain superfamily	Homologous Superfamily
K [auth S], R [auth O]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
K [auth S], R [auth O]	IPR047575	Sm domain	Domain
K [auth S], R [auth O]	IPR010920	LSM domain superfamily	Homologous Superfamily
L [auth T], S [auth P]	IPR027141	Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3	Family
L [auth T], S [auth P]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
L [auth T], S [auth P]	IPR047575	Sm domain	Domain
L [auth T], S [auth P]	IPR010920	LSM domain superfamily	Homologous Superfamily
M [auth U], T [auth Q]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
M [auth U], T [auth Q]	IPR047575	Sm domain	Domain
M [auth U], T [auth Q]	IPR027248	Small nuclear ribonucleoprotein Sm D2	Family
M [auth U], T [auth Q]	IPR010920	LSM domain superfamily	Homologous Superfamily
N [auth V], U [auth Y]	IPR027078	Small nuclear ribonucleoprotein E	Family
N [auth V], U [auth Y]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
N [auth V], U [auth Y]	IPR047575	Sm domain	Domain
N [auth V], U [auth Y]	IPR010920	LSM domain superfamily	Homologous Superfamily
O [auth W], V [auth Z]	IPR016487	Sm-like protein Lsm6/SmF	Family
O [auth W], V [auth Z]	IPR034100	Small nuclear ribonucleoprotein F	Family
O [auth W], V [auth Z]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
O [auth W], V [auth Z]	IPR047575	Sm domain	Domain
O [auth W], V [auth Z]	IPR010920	LSM domain superfamily	Homologous Superfamily
P [auth X], W [auth a]	IPR044641	Sm-like protein Lsm7/SmG	Family
P [auth X], W [auth a]	IPR034098	Small nuclear ribonucleoprotein G	Family
P [auth X], W [auth a]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
P [auth X], W [auth a]	IPR047575	Sm domain	Domain
P [auth X], W [auth a]	IPR010920	LSM domain superfamily	Homologous Superfamily
X [auth b]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
X [auth b]	IPR047575	Sm domain	Domain
X [auth b]	IPR034103	Sm-like protein Lsm8	Domain
X [auth b]	IPR010920	LSM domain superfamily	Homologous Superfamily
X [auth b]	IPR044642	U6 snRNA-associated Sm-like protein Lsm1/8	Family
Y [auth c]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
Y [auth c]	IPR047575	Sm domain	Domain
Y [auth c]	IPR010920	LSM domain superfamily	Homologous Superfamily
Y [auth c]	IPR016654	U6 snRNA-associated Sm-like protein LSm2	Family
Z [auth d]	IPR040002	U6 snRNA-associated Sm-like protein Lsm3	Family
Z [auth d]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
Z [auth d]	IPR047575	Sm domain	Domain
Z [auth d]	IPR010920	LSM domain superfamily	Homologous Superfamily
Z [auth d]	IPR034105	Sm-like protein Lsm3	Domain
AA [auth e]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
AA [auth e]	IPR047575	Sm domain	Domain
AA [auth e]	IPR016487	Sm-like protein Lsm6/SmF	Family
AA [auth e]	IPR010920	LSM domain superfamily	Homologous Superfamily
BA [auth f]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
BA [auth f]	IPR047575	Sm domain	Domain
BA [auth f]	IPR033871	Sm-like protein LSm5	Domain
BA [auth f]	IPR010920	LSM domain superfamily	Homologous Superfamily
CA [auth g]	IPR044641	Sm-like protein Lsm7/SmG	Family
CA [auth g]	IPR017132	Sm-like protein Lsm7	Family
CA [auth g]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
CA [auth g]	IPR047575	Sm domain	Domain
CA [auth g]	IPR010920	LSM domain superfamily	Homologous Superfamily
DA [auth h]	IPR001163	Sm domain, eukaryotic/archaea-type	Domain
DA [auth h]	IPR027141	Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3	Family
DA [auth h]	IPR047575	Sm domain	Domain
DA [auth h]	IPR034101	Sm-like protein Lsm4	Domain
DA [auth h]	IPR010920	LSM domain superfamily	Homologous Superfamily