6H3K
Introduction of a methyl group curbs metabolism of pyrido[3,4-d]pyrimidine MPS1 inhibitors and enables the discovery of the Phase 1 clinical candidate BOS172722.
Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.
Version Number | Version Date | Version Type/Reason | Version Change | Revised CIF Category | |
---|---|---|---|---|---|
1.0 | 2018-09-19 | Initial release | |||
1.1 | 2018-10-10 | Data collection, Database references | citation | Download |