5AAU

Optimization of a novel binding motif to to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (AZD9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist


Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.


Version NumberVersion DateVersion Type/Reason Version ChangeRevised CIF Category
1.02015-10-14Initial release
1.12015-11-04Database references
1.22016-10-12Database references
1.32024-05-01Data collection, Database references, Derived calculations, Other, Refinement descriptionchem_comp_atom, chem_comp_bond, database_2, pdbx_database_status, pdbx_initial_refinement_model, struct_site Download