4Y8Z

Factor XIa in complex with the inhibitor (2E)-N-[(1S)-1-[5-chloro-4-(4-hydroxy-2-oxo-1,2-dihydroquinolin-6-yl)-1H-imidazol-2-yl]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enamide

Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.

Version Number	Version Date	Version Type/Reason	Version Change	Revised CIF Category
1.0	2015-05-27	Initial release
1.1	2018-04-18		Data collection, Database references, Derived calculations, Source and taxonomy, Structure summary	chem_comp, citation, citation_author, entity, entity_src_gen, pdbx_entity_nonpoly, pdbx_struct_oper_list
1.2	2023-09-27		Data collection, Database references, Derived calculations, Refinement description, Structure summary	chem_comp, chem_comp_atom, chem_comp_bond, database_2, entity, pdbx_entity_nonpoly, pdbx_initial_refinement_model	Download

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.