4ANB
Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518 (GDC-0973), or related analogs.
Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.
| Version Number | Version Date | Version Type/Reason | Version Change | Revised CIF Category | |
|---|---|---|---|---|---|
| 1.0 | 2012-12-19 | Initial release | |||
| 1.1 | 2014-06-18 | Database references | Download | ||
| 2.0 | 2018-06-20 | Advisory, Atomic model, Data collection, Derived calculations | atom_site, pdbx_nonpoly_scheme, pdbx_struct_conn_angle, pdbx_struct_sheet_hbond, pdbx_validate_close_contact, pdbx_validate_symm_contact, struct_conf, struct_conn, struct_conn_type, struct_sheet, struct_sheet_order, struct_sheet_range, struct_site, struct_site_gen | ||
| 2.1 | 2019-05-08 | Data collection, Experimental preparation | exptl_crystal_grow | Download |
