4AN9

Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518 (GDC-0973), or related analogs.


Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.


Version NumberVersion DateVersion Type/Reason Version ChangeRevised CIF Category
1.02012-12-19Initial release
1.12014-06-18Database references
1.22018-06-20Data collection, Derived calculationspdbx_struct_conn_angle, struct_conn, struct_conn_type
1.32019-05-08Data collection, Experimental preparationexptl_crystal_grow Download