3R92

Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.

Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.

Version Number	Version Date	Version Type/Reason	Version Change	Revised CIF Category
1.0	2011-06-08	Initial release
1.1	2011-07-13		Version format compliance
1.2	2020-04-15		Data collection, Database references	reflns, struct_ref_seq_dif
1.3	2024-02-21		Data collection, Database references, Derived calculations	chem_comp_atom, chem_comp_bond, database_2, struct_site	Download

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3R92

Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.