Download MendeleyFragment of 7SK snRNA methylphosphate capping enzyme
Wu, H., Tempel, W., Dombrovski, L., McCarthy, A.A., Loppnau, P., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Park, H., Structural Genomics Consortium (SGC)To be published.
5UNA
Fragment of 7SK snRNA methylphosphate capping enzyme
- PDB DOI: https://doi.org/10.2210/pdb5UNA/pdb
- Entry: 5UNA supersedes: 3G07
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2017-01-30 Released: 2017-03-08
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.55 Å
- R-Value Free: 0.217
- R-Value Work: 0.204
- R-Value Observed: 0.204
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 7SK snRNA methylphosphate capping enzyme | 292 | Homo sapiens | Mutation(s): 0 Gene Names: MEPCE, BCDIN3 EC: 2.1.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q7L2J0 (Homo sapiens) Explore Q7L2J0 Go to UniProtKB: Q7L2J0 | |||||
PHAROS: Q7L2J0 GTEx: ENSG00000146834 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q7L2J0 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| unidentified peptide section/fragment | G [auth M], H [auth N], I [auth O], J [auth Q], K [auth R] | 6 | Homo sapiens | Mutation(s): 0 |  |
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SAH Query on SAH | L [auth A] M [auth B] N [auth C] O [auth D] P [auth E] | S-ADENOSYL-L-HOMOCYSTEINE C14 H20 N6 O5 S ZJUKTBDSGOFHSH-WFMPWKQPSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| MSE Query on MSE | A, B, C, D, E A, B, C, D, E, F | L-PEPTIDE LINKING | C5 H11 N O2 Se |  | MET |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.55 Å
- R-Value Free: 0.217
- R-Value Work: 0.204
- R-Value Observed: 0.204
- Space Group: H 3
- Diffraction Data: https://doi.org/10.18430/M35UNA
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 183.24 | α = 90 |
| b = 183.24 | β = 90 |
| c = 151.39 | γ = 120 |
| Software Name | Purpose |
|---|---|
| BUSTER | refinement |
| Aimless | data scaling |
| PDB_EXTRACT | data extraction |
| XDS | data reduction |
| SOLVE | phasing |
Entry History
Deposition Data
- Released Date: 2017-03-08 Deposition Author(s): Wu, H., Tempel, W., Dombrovski, L., McCarthy, A.A., Loppnau, P., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Park, H., Structural Genomics Consortium (SGC)
- This entry supersedes: 3G07
Revision History (Full details and data files)
- Version 1.0: 2017-03-08
Type: Initial release
