New insights into the molecular mechanism of the Rab GTPase Sec4p activation.
Rinaldi, F.C., Packer, M., Collins, R.(2015) BMC Struct Biol 15: 14-14
- PubMed: 26263895 
- DOI: https://doi.org/10.1186/s12900-015-0041-5
- Primary Citation of Related Structures:  
4Z8Y, 4ZDW - PubMed Abstract: 
Sec4p is a small monomeric Ras-related GTP-binding protein (23 kDa) that regulates polarized exocytosis in S. cerevisiae. In this study we examine the structural effects of a conserved serine residue in the P-loop corresponding to G12 in Ras.
Organizational Affiliation: 
Department of Molecular Medicine, Cornell University, Ithaca, NY, 14853, USA. fcr23@cornell.edu.