The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1.
Hu, J., Wu, Y., Li, J., Qian, X., Fu, Z., Sha, B.(2008) BMC Struct Biol 8: 3-3
- PubMed: 18211704 
- DOI: https://doi.org/10.1186/1472-6807-8-3
- Primary Citation of Related Structures:  
2QLD - PubMed Abstract: 
The mechanism by which Hsp40 and other molecular chaperones recognize and interact with non-native polypeptides is a fundamental question. How Hsp40 co-operates with Hsp70 to facilitate protein folding is not well understood. To investigate the mechanisms, we determined the crystal structure of the putative peptide-binding fragment of Hdj1, a human member of the type II Hsp40 family.
Organizational Affiliation: 
Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. hujunbin@uab.edu