Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution.
Kiefer, J.R., Mao, C., Hansen, C.J., Basehore, S.L., Hogrefe, H.H., Braman, J.C., Beese, L.S.(1997) Structure 5: 95-108
- PubMed: 9016716 
- DOI: https://doi.org/10.1016/s0969-2126(97)00169-x
- Primary Citation of Related Structures:  
1XWL - PubMed Abstract: 
The study of DNA polymerases in the Pol l family is central to the understanding of DNA replication and repair. DNA polymerases are used in many molecular biology techniques, including PCR, which require a thermostable polymerase. In order to learn about Pol I function and the basis of thermostability, we undertook structural studies of a new thermostable DNA polymerase.
Organizational Affiliation: 
Department of Biochemistry, Duke University Medical Centre, Durham, NC 27710, USA.