Phosducin induces a structural change in transducin beta gamma.
Loew, A., Ho, Y.K., Blundell, T., Bax, B.(1998) Structure 6: 1007-1019
- PubMed: 9739091 
- DOI: https://doi.org/10.1016/s0969-2126(98)00102-6
- Primary Citation of Related Structures:  
1A0R - PubMed Abstract: 
Phosducin binds tightly to the beta gamma subunits (Gt beta gamma) of the heterotrimeric G protein transducin, preventing Gt beta gamma reassociation with Gt alpha-GDP and thereby inhibiting the G-protein cycle. Phosducin-like proteins appear to be widely distributed and may play important roles in regulating many heterotrimeric G-protein signaling pathways.
Organizational Affiliation: 
Department of Biochemistry and Molecular Biology, University of Illinois at Chicago, IL 60612-7334, USA.