Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Wagner, J.M., Chan, S., Evans, T.J., Kahng, S., Kim, J., Arbing, M.A., Eisenberg, D., Korotkov, K.V.(2016) BMC Struct Biol 16: 5-5
- PubMed: 26922638 
- DOI: https://doi.org/10.1186/s12900-016-0056-6
- Primary Citation of Related Structures:  
4KK7, 4KV2, 4KV3, 5CYU - PubMed Abstract: 
The ESX-1 type VII secretion system is an important determinant of virulence in pathogenic mycobacteria, including Mycobacterium tuberculosis. This complicated molecular machine secretes folded proteins through the mycobacterial cell envelope to subvert the host immune response. Despite its important role in disease very little is known about the molecular architecture of the ESX-1 secretion system.
Organizational Affiliation: 
Department of Molecular & Cellular Biochemistry and Center for Structural Biology, University of Kentucky, 741 South Limestone, Lexington, KY, 40536, USA. jonw7782@gmail.com.