Structure-Based Mutational Analysis of Eif4E in Relation to Sbm1 Resistance to Pea Seed-Borne Mosaic Virus in Pea.
Ashby, J.A., Stevenson, C.E., Jarvis, G.E., Lawson, D.M., Maule, A.J.(2011) PLoS One 6: E873
- PubMed: 21283665 
- DOI: https://doi.org/10.1371/journal.pone.0015873
- Primary Citation of Related Structures:  
2WMC - PubMed Abstract: 
Pea encodes eukaryotic translation initiation factor eIF4E (eIF4E(S)), which supports the multiplication of Pea seed-borne mosaic virus (PSbMV). In common with hosts for other potyviruses, some pea lines contain a recessive allele (sbm1) encoding a mutant eIF4E (eIF4E(R)) that fails to interact functionally with the PSbMV avirulence protein, VPg, giving genetic resistance to infection.
Organizational Affiliation: 
Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.