Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2

UniProtKB accession:  Q9ZPI5

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UniProtKB description:  Involved in peroxisomal fatty acid beta-oxidation during seed germination. Possesses enoyl-CoA hydratase activity against long chain substrates (C14-C18) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C18) (PubMed:10521521, PubMed:16507084, PubMed:20463021). Possesses 3-hydroxy-3-phenylpropionyl-CoA dehydrogenase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of substituted hydroxybenzoylated choline esters, which are BA-containing secondary metabolites (PubMed:24254312). Fatty acid beta-oxidation pathway in peroxisomes regulates gene silencing, histone acetylation and DNA methylation (PubMed:31064880).