Poly [ADP-ribose] polymerase 1
UniProtKB accession: Q9ZP54
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Go to UniProtKB: Q9ZP54
UniProtKB description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity).
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