Suppressor of tumorigenicity 14 protein

UniProtKB accession:  Q9Y5Y6

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site (PubMed:10373424). Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing (PubMed:18843291). Proteolytically cleaves and therefore activates TMPRSS13 (PubMed:28710277).