SUMO-activating enzyme subunit 2
UniProtKB accession: Q9UBT2
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Go to UniProtKB: Q9UBT2
UniProtKB description: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
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