Histone-lysine N-methyltransferase family member SUVH9

UniProtKB accession:  Q9T0G7

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Histone methyltransferase family member that plays a role in gene silencing (PubMed:19043555, PubMed:24463519, PubMed:27171427). Together with MORC6 and SUVH2, regulates the silencing of some transposable elements (TEs) (PubMed:27171427). According to PubMed:19043555, the protein does not bind S-adenosyl-L-methionine and lacks methyltransferase activity. Instead, it may function downstream of DRM2 in RNA-directed DNA methylation, binding to methylated DNA and recruiting DNA-directed RNA polymerase V to chromatin (PubMed:24463519, PubMed:27171427).