NAD/NADP-dependent betaine aldehyde dehydrogenase

UniProtKB accession:  Q9HTJ1

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid. In P.aeruginosa this reaction is a compulsory step in the assimilation of carbon and nitrogen when bacteria are growing in choline or choline precursors. Can use NADP(+) with similar efficiency to NAD(+), a property that can be used by the bacterium to produce the NADPH needed to combat the oxidative stress imposed by the host defenses.