Dedicator of cytokinesis protein 5
UniProtKB accession: Q9H7D0
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Go to UniProtKB: Q9H7D0
UniProtKB description: Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).
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