1,3,6,8-tetrahydroxynaphthalene synthase

UniProtKB accession:  Q9FCA7

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Involved in the biosynthesis of melanin but also various secondary metabolites containing a naphthoquinone ring. Catalyzes the iterative condensation of five CoA-linked malonyl units to form a pentaketide intermediate. THNS subsequently catalyzes the dual intramolecular Claisen and aldol condensations of this linear intermediate to produce the fused ring of 1,3,6,8-tetrahydroxynaphthalene (THN).