Tyrosine-protein kinase FRK
UniProtKB accession: Q922K9
Grouped By: Matching UniProtKB accession
Group Content:
Go to UniProtKB: Q922K9
UniProtKB description: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
Group Members:
Release Date:
Structure Features
Sequence Features
Experimental Features
Organisms
Protein Domains
Function
