Histone deacetylase 15

UniProtKB accession:  Q8GXJ1

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (PubMed:23548744). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (PubMed:23548744). Histone deacetylases act via the formation of large multiprotein complexes (Probable). Represses chlorophyll biosynthesis and photosynthesis in the dark (PubMed:23548744). Is recruited by PIF3 to the promoters of chlorophyll biosynthetic and photosynthetic genes, and represses their transcription by histone deacetylation (PubMed:23548744). Involved in the repression of hypocotyl cell elongation to promote photomorphogenesis (PubMed:31061103). Is recruited by HY5 to the promoters of a subset of cell wall organization and auxin signaling-related genes, and represses gene expression by decreasing the levels of histone H4 acetylation in a light-dependent manner (PubMed:31061103). Promotes abscisic acid (ABA) signaling (PubMed:30979883). Is recruited by MYB96 to the promoters of a subset of Rho GTPase (ROP) genes, which repress ABA signaling at the early stages of signal transduction (PubMed:30979883). Represses ROP expression by removing acetyl groups of histone H3 and H4 from the cognate regions, particularly in the presence of ABA (PubMed:30979883). Represses the plant response to elevated ambient temperature by directly repressing warm temperature-responsive genes (PubMed:31400169).