F-box only protein 43

UniProtKB accession:  Q8CDI2

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (PubMed:16456547). Plays a vital role in modulating the ubiquitilation of CCNB1 and CDK1 during gametogenesis (PubMed:28723571).