Piezo-type mechanosensitive ion channel component 2

UniProtKB accession:  Q8CD54

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UniProtKB description:  Pore-forming subunit of a mechanosensitive non-specific cation channel required for rapidly adapting mechanically activated (MA) currents and has a key role in sensing touch and tactile pain (PubMed:20813920, PubMed:24717433). Required for Merkel-cell mechanotransduction (PubMed:24717433). Plays a major role in light-touch mechanosensation (PubMed:25471886).