Lysine-specific demethylase 5B
UniProtKB accession: Q80Y84
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Go to UniProtKB: Q80Y84
UniProtKB description: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
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