Lebetin-2-alpha

UniProtKB accession:  Q7LZ09

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UniProtKB description:  Inhibits platelet aggregation induced by thrombin, collagen and PAF-acether (PubMed:8769304, PubMed:9839678). Human platelet aggregation induced by thrombin is inhibited by synthetic lebetin-1-alpha with (IC(50)=140 nM) (PubMed:11910186). In vivo, inhibits collagen-induced thrombocytopenia in rats (PubMed:8769304, PubMed:9839678). Is not toxic upon intravenous injection into mice and rats (PubMed:8769304).