Ribonucleoside-diphosphate reductase subunit M2 B
UniProtKB accession: Q7LG56
Grouped By: Matching UniProtKB accession
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Go to UniProtKB: Q7LG56
UniProtKB description: Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
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