A-kinase anchor protein 7 isoforms delta and gamma
UniProtKB accession: Q6JP77
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Go to UniProtKB: Q6JP77
UniProtKB description: Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium (By similarity). Isoform Delta may be involved in shuttling aquaporin-2 (AQP2) to the plasma membrane.
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