Guanine nucleotide exchange factor BopE
UniProtKB accession: Q63K41
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Go to UniProtKB: Q63K41
UniProtKB description: Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells.
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