RNA-binding E3 ubiquitin-protein ligase MEX3C
UniProtKB accession: Q5U5Q3
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Go to UniProtKB: Q5U5Q3
UniProtKB description: E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
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