N-acetyltransferase ESCO1

UniProtKB accession:  Q5FWF5

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Acetyltransferase required for the establishment of sister chromatid cohesion (PubMed:15958495, PubMed:18614053). Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3 (PubMed:18614053).