D-alanyl-D-alanine carboxypeptidase

UniProtKB accession:  Q47746

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Carboxypeptidase that cleaves the C-terminal D-alanine residue from the peptidoglycan-derived pentapeptide L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala in vitro. Therefore, should contribute in vivo to the hydrolysis of the D-alanyl-D-alanine-containing peptidoglycan precursors. May increase the level of glycopeptide antibiotics resistance by decreasing the availability of D-Ala-D-Ala termini from the cell surface, which constitute the antibiotic target residues.