Cytolethal distending toxin subunit B
UniProtKB accession: Q46669
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Go to UniProtKB: Q46669
UniProtKB description: Part of the tripartite complex that is required for the CDT activity. CdtB exhibits a DNA-nicking endonuclease activity, and very probably causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement.
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