Protein tost-1

UniProtKB accession:  Q18490

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Component of the tost-1 variant of the PETISCO complex which plays an essential role in embryogenesis (PubMed:31147388, PubMed:31216475). Within the complex acts as an adapter which binds to the complex via erh-2 (PubMed:31147388). Does not seem to play a role in the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) (PubMed:31147388). May inhibit 21U-RNA accumulation (PubMed:31216475). Required for chromosome segregation and cell division in early embryos (PubMed:31216475).