Protein patched homolog 1

UniProtKB accession:  Q13635

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.