Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
UniProtKB accession: Q13155
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Go to UniProtKB: Q13155
UniProtKB description: Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed:19131329). Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
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