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Mitogen-activated protein kinase kinase kinase 12

UniProtKB accession:  Q12852
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Go to UniProtKB:  Q12852
UniProtKB description:  Part of a non-canonical MAPK signaling pathway (PubMed:28111074). Activated by APOE, enhances the AP-1-mediated transcription of APP, via a MAP kinase signal transduction pathway composed of MAP2K7 and MAPK1/ERK2 and MAPK3/ERK1 (PubMed:28111074). May be an activator of the JNK/SAPK pathway.
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