Fem-3 mRNA-binding factor 2
UniProtKB accession: Q09312
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Go to UniProtKB: Q09312
UniProtKB description: Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline (PubMed:9393998). May also play a role in the hermaphrodite germline proliferation and oogenesis (PubMed:15454534, PubMed:27864381). By binding to the 3'-UTR, represses phosphatase lip-1 expression in the distal part of the germline mitotic zone (PubMed:16319922). Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch (PubMed:9393998). Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform b 3'-UTR (PubMed:15454534). Suppresses germline tumor formation by preventing the dedifferentiation of secondary spermatocytes (PubMed:22820175).
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