Oxygen sensor histidine kinase response regulator DevS/DosS

UniProtKB accession:  P9WGK2

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Member of the two-component regulatory system DevR/DevS (DosR/DosS) involved in onset of the dormancy response. Regulates an approximately 48-member regulon (PubMed:12953092). Required for full induction of the DevR (DosR) regulon; acts later than DosT to positively regulate expression of the DevR regulon during adaptation to anaerobiosis (By similarity). Characterized as an oxygen sensor; O(2) acts as a switch, with O(2)-bound Fe(2+) protein inactive in autophosphorylation (By similarity). Has also been suggested to act as a redox sensor, or perhaps as a dual oxygen/redox sensor (By similarity). Donates a phosphate group to transcriptional regulator DevR (DosR) (By similarity).